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本文引用的文献

1
Transfusion strategies for acute upper gastrointestinal bleeding.急性上消化道出血的输血策略。
N Engl J Med. 2013 Jan 3;368(1):11-21. doi: 10.1056/NEJMoa1211801.
2
Impact of blood product transfusion on short and long-term survival after cardiac surgery: more evidence.输血对心脏手术后短期和长期生存的影响:更多证据。
Ann Thorac Surg. 2012 Aug;94(2):460-7. doi: 10.1016/j.athoracsur.2012.04.005. Epub 2012 May 23.
3
Advance targeted transfusion in anemic cardiac surgical patients for kidney protection: an unblinded randomized pilot clinical trial.针对贫血心脏手术患者的肾脏保护进行提前靶向输血:一项非盲随机临床试验。
Anesthesiology. 2012 Mar;116(3):613-21. doi: 10.1097/ALN.0b013e3182475e39.
4
Liberal or restrictive transfusion in high-risk patients after hip surgery.髋关节手术后高危患者的自由输血或限制性输血。
N Engl J Med. 2011 Dec 29;365(26):2453-62. doi: 10.1056/NEJMoa1012452. Epub 2011 Dec 14.
5
Reducing noninfectious risks of blood transfusion.降低输血的非传染性风险。
Anesthesiology. 2011 Sep;115(3):635-49. doi: 10.1097/ALN.0b013e31822a22d9.
6
2011 update to the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists blood conservation clinical practice guidelines.2011 年更新版胸外科医师学会和心血管麻醉医师学会的血液保护临床实践指南。
Ann Thorac Surg. 2011 Mar;91(3):944-82. doi: 10.1016/j.athoracsur.2010.11.078.
7
Blood transfusion as a quality indicator in cardiac surgery.心脏手术中输血作为一项质量指标
JAMA. 2010 Oct 13;304(14):1610-1. doi: 10.1001/jama.2010.1483.
8
Variation in use of blood transfusion in coronary artery bypass graft surgery.冠状动脉旁路移植手术中输血使用的变化。
JAMA. 2010 Oct 13;304(14):1568-75. doi: 10.1001/jama.2010.1406.
9
Transfusion requirements after cardiac surgery: the TRACS randomized controlled trial.心脏手术后的输血需求:TRACS 随机对照试验。
JAMA. 2010 Oct 13;304(14):1559-67. doi: 10.1001/jama.2010.1446.
10
The impact of blood conservation on outcomes in cardiac surgery: is it safe and effective?血液保护对心脏手术结果的影响:它安全有效吗?
Ann Thorac Surg. 2010 Aug;90(2):451-8. doi: 10.1016/j.athoracsur.2010.04.089.

披露医师具体行为可提高心脏手术用血管理方案的依从性。

Disclosure of physician-specific behavior improves blood utilization protocol adherence in cardiac surgery.

机构信息

Division of Cardiac Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland.

出版信息

Ann Thorac Surg. 2013 Dec;96(6):2168-74. doi: 10.1016/j.athoracsur.2013.06.080. Epub 2013 Sep 12.

DOI:10.1016/j.athoracsur.2013.06.080
PMID:24035308
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4139284/
Abstract

BACKGROUND

Evidence indicates that a transfusion (Tx) trigger hemoglobin (Hgb) value of 8 gm/dL may be safer than a more liberal Tx trigger in cardiac surgery (CS) patients. We hypothesized that weekly physician feedback would improve adherence to such a protocol, but that the public identification of individual physician behavior would have an additive effect.

METHODS

We concurrently reviewed all adult CS patients at our institution from December 1, 2010 to May 27, 2011. We matched any cardiac surgery intensive care unit Tx event (red blood cells) with the Hgb value immediately before Tx. Patients requiring massive transfusions (>10 units/24 hours) were excluded. After all providers agreed upon a Hgb of 8 as the Tx trigger, we studied 3 consecutive time periods: no feedback, weekly feedback of group Tx behavior, and weekly feedback with identification of individual surgeon Tx behavior.

RESULTS

Of the 512 patients who underwent cardiac operations, 144 patients underwent 510 Tx events. Compared with period 1, the unadjusted odds of receiving a Tx above 8 gm/dL decreased by 48% in study period 2(odds ratio: 0.52, p < 0.01), and 63% in study period 3(odds ratio: 0.37, p <0.001). Single unit transfusion rates increased from 77% to greater than 90% (p < 0.001). In-hospital mortality also fell from period 1 to period 3 (7.0% to 1.5%, p = 0.02) with the observed to expected mortality ratio decreasing from 2.19 to 0.51.

CONCLUSIONS

Blood transfusion protocol adherence improves when weekly feedback is provided. Identifying individual surgeon behavior improves adherence to a greater degree. Routine presentation of quality metrics with identification of individual physician-specific behavior may be the most effective way to accomplish performance improvement.

摘要

背景

有证据表明,在心脏手术(CS)患者中,输血(Tx)触发血红蛋白(Hgb)值为 8 克/分升可能比更宽松的 Tx 触发更安全。我们假设每周向医生提供反馈将提高对该方案的遵守程度,但公开识别医生的个人行为会产生额外的效果。

方法

我们同时回顾了 2010 年 12 月 1 日至 2011 年 5 月 27 日期间我院所有成年 CS 患者。我们将心脏外科重症监护病房的任何 Tx 事件(红细胞)与 Tx 前的 Hgb 值进行匹配。排除需要大量输血(> 10 单位/24 小时)的患者。在所有提供者都同意将 8 作为 Tx 触发值后,我们研究了 3 个连续的时间段:没有反馈、每周反馈群体 Tx 行为,以及每周反馈并识别单个外科医生 Tx 行为。

结果

在接受心脏手术的 512 名患者中,有 144 名患者接受了 510 次 Tx 事件。与第 1 期相比,第 2 期研究(优势比:0.52,p < 0.01)和第 3 期研究(优势比:0.37,p < 0.001)接受 Tx 超过 8 克/分升的几率分别降低了 48%和 63%。单次输血率从 77%增加到 90%以上(p < 0.001)。住院死亡率也从第 1 期下降到第 3 期(从 7.0%下降到 1.5%,p = 0.02),观察到的与预期的死亡率比值从 2.19 下降到 0.51。

结论

当提供每周反馈时,输血方案的遵守程度会提高。更详细地识别医生的个人行为会提高遵守程度。常规呈现质量指标并识别医生的个人行为可能是实现绩效改进的最有效方法。