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[自体脂肪移植在疼痛性瘢痕手术治疗中的初步结果]

[Autologous fat grafting in the surgical management of painful scar: preliminary results].

作者信息

Baptista C, Iniesta A, Nguyen P, Legré R, Gay A-M

机构信息

Service de chirurgie de la main, chirurgie plastique et réparatrice des membres, hôpital de la Conception, 147, boulevard Baille, 13005 Marseille, France.

出版信息

Chir Main. 2013 Oct;32(5):329-34. doi: 10.1016/j.main.2013.07.006. Epub 2013 Aug 12.

DOI:10.1016/j.main.2013.07.006
PMID:24035685
Abstract

The purpose of this study was to report our experience about the effectiveness of autologous fat injections in the management of painful scars. Between 2010 and 2012, all patients with persistent incisional pain despite a well-conduced 6 months medical treatment received an autologous fat graft according to the technique originally described by Coleman. Results interpretation was based on pain improvement thanks to a Visual Analogic Scale (VAS), postoperative patient satisfaction, reduction on analgesics intake and quality of life improvement. Eleven patients were included, the mean quantity of fat injected was 11cm(3). Nine patients (1.5%) benefited from a complete or significant pain decrease, 74.5% reported being very satisfied or satisfied with the result. The mean reduction of VAS was 3.5 points. We did not observe any complication. Autologous fat grafting is an innovative therapeutic approach and appears to be an attractive concept in the management of scar neuromas resistant to drug treatment, by providing an easy effective and safe surgical treatment.

摘要

本研究的目的是报告我们在自体脂肪注射治疗疼痛性瘢痕方面的经验。在2010年至2012年期间,所有尽管接受了为期6个月的规范药物治疗但仍有持续性切口疼痛的患者,均按照科尔曼最初描述的技术接受了自体脂肪移植。结果解读基于视觉模拟评分法(VAS)评估的疼痛改善情况、术后患者满意度、镇痛药摄入量的减少以及生活质量的改善。纳入了11例患者,平均注射脂肪量为11立方厘米。9例患者(81.5%)疼痛完全缓解或显著减轻,74.5%的患者报告对结果非常满意或满意。VAS平均降低3.5分。我们未观察到任何并发症。自体脂肪移植是一种创新的治疗方法,通过提供一种简便、有效且安全的手术治疗方式,在治疗药物难治性瘢痕瘤方面似乎是一个有吸引力的概念。

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引用本文的文献

1
Effectiveness of Autologous Fat Transfer in the Treatment of Scar-Related Conditions: A Systematic Review and Meta-analysis.自体脂肪移植治疗瘢痕相关疾病的疗效:系统评价和荟萃分析。
Aesthetic Plast Surg. 2022 Oct;46(5):2564-2572. doi: 10.1007/s00266-022-02869-9. Epub 2022 Apr 11.
2
The Use of Adipose-Derived Stem Cells (ADSCs) and Stromal Vascular Fraction (SVF) in Skin Scar Treatment-A Systematic Review of Clinical Studies.脂肪来源干细胞(ADSCs)和基质血管成分(SVF)在皮肤瘢痕治疗中的应用——临床研究的系统评价
J Clin Med. 2021 Aug 17;10(16):3637. doi: 10.3390/jcm10163637.
3
Outcome of Stromal Vascular Fraction-Enriched Fat Grafting Compared to Intramuscular Transposition in Painful End-Neuromas of Superficial Radial Nerve: Preliminary Results.
与桡神经浅支疼痛性终末神经瘤肌内转位相比,富含基质血管成分脂肪移植的结果:初步结果
Front Surg. 2018 Feb 16;5:10. doi: 10.3389/fsurg.2018.00010. eCollection 2018.
4
Autologous Fat Grafting as a Last Resort for Unsustainable Pain in a Woman with Multiple Osteochondromas.自体脂肪移植作为一名患有多发性骨软骨瘤女性难以忍受疼痛的最后手段
Arch Plast Surg. 2017 Mar;44(2):162-165. doi: 10.5999/aps.2017.44.2.162. Epub 2017 Mar 15.