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短肢骨骼发育不良:超声与放射成像对胎儿脊柱的评估

Short-limb skeletal dysplasias: evaluation of the fetal spine with sonography and radiography.

作者信息

Rouse G A, Filly R A, Toomey F, Grube G L

机构信息

Department of Radiation Sciences, School of Medicine, Loma Linda University, CA 92354.

出版信息

Radiology. 1990 Jan;174(1):177-80. doi: 10.1148/radiology.174.1.2403680.

DOI:10.1148/radiology.174.1.2403680
PMID:2403680
Abstract

Sonograms and radiographs of the lumbar spine in 51 fetuses and neonates with thanatophoric dwarfism, achondroplasia, and osteogenesis imperfecta type II were retrospectively evaluated. Study data included 27 prenatal and 27 neonatal sonograms and radiographs in 40 fetuses and neonates and 11 cases described in the radiology literature. To precisely compare the sonographic and radiographic appearances of platyspondyly in dysplasia, a simple vertebral ratio was obtained from measurement of vertebral interspace and vertebral body height. Normal ranges were obtained from sonograms in 125 normal fetuses and from radiographs in 55 normal fetuses. The severe platyspondyly of thanatophoric dysplasia and the milder platyspondyly of achondroplasia were detected by about 20 menstrual weeks. The vertebral bodies appeared slightly larger on sonograms than on radiographs in both normal fetuses and fetuses with dysplasia.

摘要

对51例患有致死性侏儒症、软骨发育不全和II型成骨不全的胎儿及新生儿的腰椎超声图像和X线片进行了回顾性评估。研究数据包括40例胎儿及新生儿的27份产前和27份新生儿超声图像及X线片,以及放射学文献中描述的11例病例。为了精确比较发育异常中扁平椎的超声和X线表现,通过测量椎间隙和椎体高度获得了一个简单的椎体比率。正常范围来自125例正常胎儿的超声图像和55例正常胎儿的X线片。致死性发育异常的严重扁平椎和软骨发育不全的较轻扁平椎在约孕20周时被检测到。在正常胎儿和发育异常的胎儿中,超声图像上的椎体看起来都比X线片上的略大。

相似文献

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Short-limb skeletal dysplasias: evaluation of the fetal spine with sonography and radiography.短肢骨骼发育不良:超声与放射成像对胎儿脊柱的评估
Radiology. 1990 Jan;174(1):177-80. doi: 10.1148/radiology.174.1.2403680.
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Osteogenesis imperfecta type II: prenatal sonographic diagnosis.II型成骨不全症:产前超声诊断
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引用本文的文献

1
Normal development of sacrococcygeal centrum ossification centers in the fetal spine: a postmortem magnetic resonance imaging study.胎儿脊柱骶尾椎骨化中心的正常发育:一项尸体磁共振成像研究
Neuroradiology. 2018 Aug;60(8):821-833. doi: 10.1007/s00234-018-2050-0. Epub 2018 Jul 4.
2
Comparative X-ray morphometry of prenatal osteogenesis imperfecta type 2 and thanatophoric dysplasia: a contribution to prenatal differential diagnosis.2型产前成骨不全与致死性骨发育不全的X线形态计量学比较:对产前鉴别诊断的贡献
Radiol Med. 2017 Nov;122(11):880-891. doi: 10.1007/s11547-017-0784-0. Epub 2017 Jul 3.
3
Evaluating skeletal dysplasias on prenatal ultrasound: an emphasis on predicting lethality.
产前超声评估骨骼发育不良:重点在于预测致死性。
Pediatr Radiol. 2017 Feb;47(2):134-145. doi: 10.1007/s00247-016-3725-5. Epub 2016 Dec 1.
4
Thanatophoric dysplasia. Correlation among bone X-ray morphometry, histopathology, and gene analysis.致死性发育不全。骨X线形态测量、组织病理学与基因分析之间的相关性。
Skeletal Radiol. 2014 Sep;43(9):1205-15. doi: 10.1007/s00256-014-1899-1. Epub 2014 May 25.