Department of Industrial & Systems Engineering, North Carolina State University, Raleigh, North Carolina, United States of America.
PLoS One. 2013 Sep 5;8(9):e73437. doi: 10.1371/journal.pone.0073437. eCollection 2013.
To simulate national estimates of prepregnancy and gestational diabetes mellitus (GDM) in non-Hispanic white (NHW) and non-Hispanic black (NHB) women.
Prepregnancy diabetes and GDM were estimated as a function of age, race/ethnicity, and body mass index (BMI) using South Carolina live singleton births from 2004-2008. Diabetes risk was applied to a simulated population. Age, natality and BMI were assigned to women according to race- and age-specific US Census, Natality and National Health and Nutrition Examination Surveys (NHANES) data, respectively.
From 1980-2008, estimated GDM prevalence increased from 4.11% to 6.80% [2.68% (95% CI 2.58%-2.78%)] and from 3.96% to 6.43% [2.47% (95% CI 2.39%-2.55%)] in NHW and NHB women, respectively. In NHW women prepregnancy diabetes prevalence increased 0.90% (95% CI 0.85%-0.95%) from 0.95% in 1980 to 1.85% in 2008. In NHB women from 1980 through 2008 estimated prepregnancy diabetes prevalence increased 1.51% (95% CI 1.44%-1.57%), from 1.66% to 3.16%.
Racial disparities in diabetes prevalence during pregnancy appear to stem from a higher prevalence of prepregnancy diabetes, but not GDM, in NHB than NHW.
模拟非西班牙裔白人（NHW）和非西班牙裔黑人（NHB）女性的孕前和妊娠期糖尿病（GDM）的全国估计数。
利用 2004 年至 2008 年南卡罗来纳州的活产单胎数据，根据年龄、种族/族裔和体重指数（BMI）来估计孕前糖尿病和 GDM。将糖尿病风险应用于模拟人群。根据种族和年龄特定的美国人口普查、出生率和国家健康和营养检查调查（NHANES）数据，为女性分配年龄、出生率和 BMI。
1980 年至 2008 年，估计的 GDM 患病率从 4.11%增加到 6.80%[2.68%（95%CI 2.58%-2.78%）]和从 3.96%增加到 6.43%[2.47%（95%CI 2.39%-2.55%）]，分别在 NHW 和 NHB 女性中。在 NHW 女性中，孕前糖尿病的患病率从 1980 年的 0.95%增加了 0.90%（95%CI 0.85%-0.95%），到 2008 年的 1.85%。在 NHB 女性中，1980 年至 2008 年期间，估计的孕前糖尿病患病率增加了 1.51%（95%CI 1.44%-1.57%），从 1.66%增加到 3.16%。
妊娠期间糖尿病患病率的种族差异似乎源于 NHB 女性的孕前糖尿病患病率高于 NHW 女性，但 GDM 患病率并非如此。
