Brann B S, Wofsy C, Papile L A, Angelus P, Backstrom C
Department of Pediatrics, University of New Mexico School of Medicine, Albuquerque 87131.
J Ultrasound Med. 1990 Jan;9(1):9-15. doi: 10.7863/jum.1990.9.1.9.
Posthemorrhagic ventricular dilation is a common clinical problem in preterm infants who have incurred an intraventricular hemorrhage. Presently there are no clinically applicable methods to follow quantitatively the progression of ventricular dilation at bedside. We describe the in vivo validation of a method to measure ventricular volume using bedside real-time cranial ultrasonography. Six infants undergoing either serial lumbar punctures or cerebral ventricular reservoir taps for posthemorrhagic hydrocephalus were studied. The cerebrospinal fluid (CSF) volume removed ranged from 5.5 mL to 30 mL. A strong correlation was found (r2 = 0.84) between the volume of CSF removed by reservoir tap and the change in ventricular volume calculated by the ultrasound method, whereas the correlation between the volume of CSF removed at lumbar puncture and the change in ventricular volume calculated by the ultrasound method was not as strong (r2 = 0.70). Limitations and sources of error in the method are discussed. We conclude that this procedure is accurate and offers a quantitative method to follow longitudinally posthemorrhagic progressive ventricular dilation.
出血后脑室扩张是发生脑室内出血的早产儿常见的临床问题。目前尚无临床上可用于在床边定量追踪脑室扩张进展的方法。我们描述了一种使用床边实时头颅超声测量脑室容积方法的体内验证。研究了6例因出血后脑积水接受系列腰椎穿刺或脑室储液囊穿刺的婴儿。排出的脑脊液（CSF）量在5.5毫升至30毫升之间。通过储液囊穿刺排出的脑脊液量与通过超声方法计算的脑室容积变化之间发现了很强的相关性（r2 = 0.84），而腰椎穿刺时排出的脑脊液量与通过超声方法计算的脑室容积变化之间的相关性则没那么强（r2 = 0.70）。讨论了该方法的局限性和误差来源。我们得出结论，该程序准确，提供了一种纵向追踪出血后进行性脑室扩张的定量方法。
