Friedhelm B, Berner L, Dechet C, Presson A, Pycha A
Department of Urology, Central Hospital of Bolzano, Italy.
Aktuelle Urol. 2013 Sep;44(5):370-4. doi: 10.1055/s-0033-1353203. Epub 2013 Sep 16.
Benign prostate syndrome (BPS) is a common phenomenon in the aging male. Transurethral resection of the prostate (TURP) remains the international standard of care for -patients requiring surgical intervention for BPS. Although the voiding improvement following TURP is well-documented, controversy exists regarding its effect on post-operative sexual function. In this study we investigated the possible influence of individual surgeons on clinical voiding parameters and post-operative sexual function after TURP.
PATIENTS/MATERIALS AND METHODS: We analyzed 123 patients with a mean age of 70 years (46-88 years) who had undergone TURP secondary to BPS. To evaluate the clinical parameters, patients completed the IPSS and IIEF-15 questionnaires preoperatively and 1 year postoperatively. Additional parameters including urinary flow and post voiding residual volume were also collected.
A statistically significant improvement in voiding function was noted postoperatively. The mean IPSS improved from 19.35 to 6.49 (p<0.05). Objective flow parameters also improved; Qmax 10.43-19.46 mL/s (p<0.05) and residual volume 95-11 mL (p<0.05). The mean pre-operative prostate volume was 41.8 cm³. The mean resected tissue weight was 21.1 g. The pa-tients showed no significant change in the frequency of their sexual activity following TURP, however IIEF-15 sexual function and erectile function scores declined mildly. This was statistically significant with pre-op IIEF-15=30.52 and post-op 26.24 (p<0.05). Comparing individual surgeons, no statistically significant difference was noted in IPSS and IIEF-15 functional outcome scores. Although significant differences existed in the total amount of resected tissue, the percentage of resected adenoma in relation to total prostate volume was not statistically significant.
Overall, IPSS scores improved significantly following TURP and sexual function scored declined mildly. We detected no influence between surgeons on clinical voiding parameters and postoperative sexual function after TURP using the IPSS and IIEF-15 questionnaires.
良性前列腺综合征(BPS)是老年男性中的常见现象。经尿道前列腺切除术(TURP)仍是因BPS需要手术干预的患者的国际护理标准。尽管TURP术后排尿改善情况已有充分记录,但关于其对术后性功能的影响仍存在争议。在本研究中,我们调查了个体外科医生对TURP术后临床排尿参数和性功能的可能影响。
患者/材料与方法:我们分析了123例平均年龄70岁(46 - 88岁)因BPS接受TURP的患者。为评估临床参数,患者在术前和术后1年完成国际前列腺症状评分(IPSS)和国际勃起功能指数-15项问卷(IIEF - 15)。还收集了包括尿流率和残余尿量在内的其他参数。
术后排尿功能有统计学意义的改善。平均IPSS从19.35改善至6.49(p<0.05)。客观的尿流参数也有所改善;最大尿流率(Qmax)从10.43增至19.46 mL/s(p<0.05),残余尿量从95降至11 mL(p<0.05)。术前平均前列腺体积为41.8 cm³。平均切除组织重量为21.1 g。TURP术后患者的性活动频率无显著变化,然而IIEF - 15性功能和勃起功能评分略有下降。术前IIEF - 15为30.52,术后为26.24,具有统计学意义(p<0.05)。比较个体外科医生,IPSS和IIEF - 15功能结局评分无统计学显著差异。尽管切除组织总量存在显著差异,但切除腺瘤占前列腺总体积的百分比无统计学意义。
总体而言,TURP术后IPSS评分显著改善,性功能评分略有下降。使用IPSS和IIEF - 15问卷,我们未发现外科医生对TURP术后临床排尿参数和性功能有影响。