遗传性出血性毛细血管扩张症致脑栓塞的罕见病因。

A rare cause of embolic stroke in hereditary hemorrhagic telangiectasia.

机构信息

Department of Medicine, Melbourne Brain Centre at Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia; Department of Neurology, Melbourne Brain Centre at Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia.

出版信息

J Stroke Cerebrovasc Dis. 2014 May-Jun;23(5):1245-6. doi: 10.1016/j.jstrokecerebrovasdis.2013.07.037. Epub 2013 Sep 14.

DOI:10.1016/j.jstrokecerebrovasdis.2013.07.037

PMID:24045083

Abstract

A 57-year-old male patient with hereditary hemorrhagic telangiectasia presented with an acute right middle cerebral artery ischemic stroke. Investigations revealed a right middle cerebral artery M2 occlusion, hypoxemia, and a large pulmonary arteriovenous malformation and right lower limb deep venous thrombosis. Closure of the pulmonary arteriovenous malformation was successfully performed with an Amplatzer device. Catheter closure of pulmonary arteriovenous malformations in patients with hereditary hemorrhagic telangiectasia is a recognized treatment modality to prevent recurrent ischemic stroke and other embolic and hemorrhagic complications.

摘要

一位 57 岁的男性遗传性出血性毛细血管扩张症患者发生急性右侧大脑中动脉缺血性脑卒中。检查发现右侧大脑中动脉 M2 段闭塞、低氧血症、巨大肺动静脉畸形和右下肢深静脉血栓形成。使用 Amplatzer 装置成功地对肺动静脉畸形进行了封堵。对遗传性出血性毛细血管扩张症患者进行肺动静脉畸形导管封堵术是一种公认的治疗方法，可预防复发性缺血性卒中和其他栓塞及出血性并发症。