Department of Medical and Surgical Specialties and Dentistry, Second University of Naples, Naples, Italy,
Aging Clin Exp Res. 2013 Oct;25 Suppl 1:S129-31. doi: 10.1007/s40520-013-0102-1. Epub 2013 Sep 18.
We performed a pilot study with the purpose to evaluate the prevalence of sarcopenia in osteoporotic women with vertebral fractures. Dual-energy X-ray absorptiometry (DXA) was used to measure the whole and regional body composition. Appendicular lean mass (aLM) was calculated as the sum of lean mass in arms and legs. We calculated the skeletal muscle mass index (aLM/h(2)), and we measured bone mineral density and T scores by DXA scan at total-body and at femoral neck. Participants were divided according to the number of vertebral fractures (single or multiple fractures). A total of 67 women were included. Thirty-five women (52.23%) had a vertebral fracture, of them 8 (22.85%) were sarcopenic and 32 women (47.76%) had multiple vertebral fractures, of them 14 (43.75%) were sarcopenic. Our results suggest that sarcopenia is common among osteoporotic women increasing along with the number of vertebral fragility fractures.
我们进行了一项试点研究,旨在评估骨质疏松性椎体骨折女性中肌少症的患病率。双能 X 线吸收法(DXA)用于测量全身和局部的身体成分。四肢瘦体重(aLM)计算为手臂和腿部瘦体重的总和。我们计算了骨骼肌质量指数(aLM/h(2)),并通过 DXA 扫描测量全身和股骨颈的骨矿物质密度和 T 评分。参与者根据椎体骨折数量(单发或多发骨折)进行分组。共纳入 67 名女性。35 名女性(52.23%)有椎体骨折,其中 8 名(22.85%)为肌少症;32 名女性(47.76%)有多发椎体骨折,其中 14 名(43.75%)为肌少症。我们的结果表明,肌少症在骨质疏松性女性中很常见,并且随着椎体脆性骨折数量的增加而增加。