Miller I W, Norman W H, Keitner G I
Department of Psychiatry and Human Behavior, Brown University, Providence, RI.
Compr Psychiatry. 1990 Jan-Feb;31(1):62-71. doi: 10.1016/0010-440x(90)90055-w.
A sample of depressed inpatients was subdivided according to their initial levels of cognitive dysfunction. These high cognitive dysfunction (HCD) patients and low cognitive dysfunction (LCD) patients received either pharmacotherapy or combined pharmacotherapy plus cognitive-behavioral psychotherapy. Treatments began in the hospital and continued for 20 weeks on an outpatient basis. Results indicated that HCD patients had significantly better treatment response to the combined treatment than pharmacotherapy alone, while LCD patients responded equally to pharmacotherapy alone and combined treatment.
一组抑郁症住院患者根据其最初的认知功能水平进行了细分。这些高认知功能障碍（HCD）患者和低认知功能障碍（LCD）患者接受了药物治疗或药物治疗联合认知行为心理治疗。治疗在医院开始，并在门诊持续进行20周。结果表明，HCD患者接受联合治疗的治疗反应明显优于单纯药物治疗，而LCD患者对单纯药物治疗和联合治疗的反应相同。
