Eliason J A, McCulley J P
Department of Ophthalmology, Stanford University Medical Center, CA 94305.
Cornea. 1990 Jan;9(1):10-6.
A comparison between continuous and interrupted techniques of suturing in penetrating keratoplasties was made using autologous grafts in rabbits. Wound strength was determined using both a tensiometer and blow-out pressure measurements. Histologic examination of the wounds was also carried out, and clinical observations were made of the behavior of vascular growth through the wound in prevascularized corneas to further characterize the suturing techniques and the healing process. We found no difference in blow-out pressures between the two groups, but a significant increase in healing in the interrupted suture group, as measured by the tensiometer, was observed. Other differences were noted in the clinical course and histology, including a greater ease of vessels traversing the wound and more inflammatory cells in the wound area with interrupted sutures.
在兔穿透性角膜移植术中，使用自体移植物对连续缝合技术和间断缝合技术进行了比较。通过张力计和抗张强度测量来确定伤口强度。还对伤口进行了组织学检查，并对血管化角膜中伤口处血管生长的行为进行了临床观察，以进一步描述缝合技术和愈合过程。我们发现两组之间的抗张强度没有差异，但通过张力计测量，间断缝合组的愈合有显著增加。在临床过程和组织学方面还发现了其他差异，包括间断缝合时血管更易穿过伤口以及伤口区域有更多炎性细胞。
