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[预激综合征合并心房颤动患者发生心室颤动时的不典型应激性心肌病:诊断问题]

[Atypical form of tako-tsubo cardiomyopathy in a patient with atrial fibrillation in Wolff-Parkinson-White syndrome complicated with ventricular fibrillation: the diagnostic problems].

作者信息

Kukla Piotr, Stec Sebastian, Karbarz Dariusz, Wrzosek Bożena, Jastrzębski Marek, Kluczewski Maciej, Kurdzielewicz Wojciech

机构信息

Oddział Internistyczno-Kardiologiczny, Szpital Specjalistyczny, Gorlice.

出版信息

Kardiol Pol. 2013;71(8):864-8. doi: 10.5603/KP.2013.0203.

Abstract

Atypical form of tako-tsubo cardiomyopathy (TTC) is associated with regional wall motion abnormalities in basal and/or middle segments or only middle segments with sparing of apical segments or apical and basal segments. We described a case of47-year-old female with atypical form of TTC due to fast atrial fibrillation that converted into ventricular fibrillation in WPW syndrome. The echocardiogram made after direct current cardioversion revealed decreased left ventricular ejection fraction (LVEF 35%) with akinesis of inferior and posterior walls and anterior part of interventricular septum in the middle and the basal segments with hyperkinesis of apical segments. The biochemistry blood samples revealed elevated both troponin T- 0.35 ng/mL and NT-proBNP - 3550 pg/mL plasma level. The ECG showed sinus rhythm 62 bpm, shortened PQ interval 100 ms, widened QRS duration - 115 ms with delta wave, prolonged QT interval - 520 ms, QS in leads: II, III, aVF. NegativeT waves in leads: I, aVL and positive, symmetrical T waves in leads V1-V6. The coronarography revealed normal coronaryarteries. The control echocardiography after 10 days showed normal LVEF 70%, without any wall motion abnormalities. TTC was recognised based on: history of sudden stress situation before, ischaemic ECG changes, positive markers of myocardial injury, transient segmental wall motion abnormalities and normal coronary arteries. The ablation of right postero-septal accessory pathway was successfully performed.

摘要

应激性心肌病(TTC)的非典型形式与基底段和/或中间段或仅中间段的节段性室壁运动异常相关,心尖段或心尖段和基底段未受累。我们描述了一例47岁女性,患有因快速房颤导致的TTC非典型形式,该房颤在预激综合征中转变为室颤。直流电复律后进行的超声心动图显示左心室射血分数降低(LVEF 35%),中间段和基底段下壁、后壁及室间隔前部运动减弱,心尖段运动增强。生化血样显示肌钙蛋白T血浆水平升高至0.35 ng/mL,N末端B型利钠肽原血浆水平升高至3550 pg/mL。心电图显示窦性心律62次/分,PQ间期缩短至100 ms,QRS时限增宽至115 ms伴预激波,QT间期延长至520 ms,II、III、aVF导联呈QS波。I、aVL导联T波倒置,V1-V6导联T波直立、对称。冠状动脉造影显示冠状动脉正常。10天后的对照超声心动图显示左心室射血分数正常为70%,无任何室壁运动异常。TTC的诊断基于:既往突发应激情况病史、缺血性心电图改变、心肌损伤阳性标志物、短暂节段性室壁运动异常及冠状动脉正常。成功进行了右后间隔旁道消融术。

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