Dubois G, Damas F, Fraipont V
Service des Soins Intensifs, CHR Citadelle, Liège.
Rev Med Liege. 2013 Jul-Aug;68(7-8):387-90.
Lemierre's syndrome is a rare, but significant pathology to recognize. It most often affects young patients in good health; a late diagnosis can be fatal. It consists in an anaerobic septicemia (usually, Fusobacterium necrophorum) originating from a suppurative thrombophlebitis of the internal jugular vein. Infection occurs during a common sore throat and spreads by contiguity. The clinical presentation is a sepsis with pulmonary embolisations, but other sites of dissemination can also occur. Treatment consists of prolonged intravenous antibiotherapy associated with supportive therapy, if needed. Anticoagulation remains controversial. The outcome is favorable in most cases provided diagnosis and treatment are early; mortality however remains significant, around 5%.
勒米尔综合征是一种罕见但需要识别的重要病症。它最常影响健康状况良好的年轻患者；诊断延迟可能致命。它表现为一种源于颈内静脉化脓性血栓性静脉炎的厌氧败血症（通常为坏死梭杆菌）。感染在普通咽喉痛期间发生并通过蔓延传播。临床表现为伴有肺栓塞的败血症，但也可能发生其他播散部位。治疗包括必要时延长静脉抗生素治疗并辅以支持治疗。抗凝治疗仍存在争议。如果早期诊断和治疗，大多数情况下预后良好；然而死亡率仍然较高，约为5%。
