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三维可视化术前治疗规划系统在肝癌微波消融中的临床初步应用

A three-dimensional visualisation preoperative treatment planning system in microwave ablation for liver cancer: a preliminary clinical application.

机构信息

Department of Interventional Ultrasound, Chinese PLA General Hospital , Beijing , China.

出版信息

Int J Hyperthermia. 2013 Nov;29(7):671-7. doi: 10.3109/02656736.2013.834383. Epub 2013 Sep 20.

Abstract

OBJECTIVES

The aim of this study was to evaluate the clinical application value of a 3D visualisation preoperative treatment planning system in microwave ablation for liver cancer.

METHODS

From December 2011 to November 2012, 94 enrolment patients of liver cancer were divided into two groups. The 3D preoperative planning group included 36 patients with 44 lesions, who underwent microwave ablation with the aid of the self-developed 3D visualisation preoperative treatment planning system. The 2D preoperative planning group included 58 patients with 64 lesions, who underwent microwave ablation according to conventional 2D image preoperative planning methods. After microwave ablation, therapeutic efficacy was assessed by contrast-enhanced imaging during follow-up.

RESULTS

The 3D preoperative planning group had a higher success rate of first ablation than the 2D preoperative planning group (p = 0.01). There were more sessions in the 2D preoperative planning group than in the 3D preoperative planning group (p = 0.002). There were no significant differences in technique effectiveness rate between the 2D preoperative planning group (96.55%) and the 3D preoperative planning group (100%) according to the contrast-enhanced imaging follow-up after microwave ablation (p = 0.64). There were no significant differences in the rate of LTP between the 2D preoperative planning group and the 3D preoperative planning group (p = 0.64) during 3-12 months follow up (median 6 months).

CONCLUSIONS

Compared with the 2D preoperative planning group, the 3D preoperative planning group had a higher success rate of first ablation and fewer sessions. Therefore, the 3D visualisation preoperative treatment planning system has a relatively high clinical application value.

摘要

目的

本研究旨在评估 3D 可视化术前治疗规划系统在肝癌微波消融中的临床应用价值。

方法

2011 年 12 月至 2012 年 11 月,将 94 例肝癌患者分为两组。3D 术前规划组 36 例 44 个病灶,采用自行开发的 3D 可视化术前治疗规划系统行微波消融治疗;2D 术前规划组 58 例 64 个病灶,根据常规 2D 图像术前规划方法行微波消融治疗。微波消融后,通过随访增强影像评估治疗效果。

结果

3D 术前规划组首次消融成功率高于 2D 术前规划组(p=0.01)。2D 术前规划组的治疗次数多于 3D 术前规划组(p=0.002)。根据微波消融后增强影像随访,2D 术前规划组(96.55%)和 3D 术前规划组(100%)的技术有效率无显著差异(p=0.64)。2D 术前规划组和 3D 术前规划组在 3-12 个月(中位时间 6 个月)的 LTP 发生率无显著差异(p=0.64)。

结论

与 2D 术前规划组相比,3D 术前规划组首次消融成功率更高,治疗次数更少。因此,3D 可视化术前治疗规划系统具有较高的临床应用价值。

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