Coulter Ian C, Kolias Angelos G, Marcus Hani J, Ahmed Aminul I, Alli Saira, Al-Mahfoudh Rafid, Borg Anouk, Cowie Christopher J A, Hill Ciaran S, Joannides Alexis J, Jones Timothy L, Kailaya-Vasan Ahilan, Livermore James L, Narayanamurthy Harsha, Ngoga Desire, Shapey Jonathan, Tarnaris Andrew, Gregson Barbara A, Gray William P, Nelson Richard J, Hutchinson Peter J, Brennan Paul M
Department of Neurosurgery, James Cook University Hospital , Middlesbrough , UK.
Br J Neurosurg. 2014 Apr;28(2):199-203. doi: 10.3109/02688697.2013.835378. Epub 2013 Sep 23.
BACKGROUND. Chronic subdural haematoma (CSDH) is a common condition that increases in incidence with rising age. Evacuation of a CSDH is one of the commonest neurosurgical procedures; however the optimal peri-operative management, surgical technique, post-operative care and the role of adjuvant therapies remain controversial. AIM. We propose a prospective multi-centre audit in order to establish current practices, outcomes and national benchmarks for future studies. METHODS. Neurosurgical units (NSU) in the United Kingdom and Ireland will be invited to enrol patients to this audit. All adult patients aged 16 years and over with a primary or recurrent CSDH will be eligible for inclusion. OUTCOME MEASURES AND ANALYSIS. The proposed outcome measures are (1) clinical recurrence requiring re-operation within 60 days; (2) modified Rankin scale (mRS) score at discharge from NSU; (3) morbidity and mortality in the NSU; (4) destination at discharge from NSU and (5) length of stay in the NSU. Audit standards have been derived from published systematic reviews and a recent randomised trial. The proposed standards are clinical recurrence rate < 20%; unfavourable mRS (4-6) at discharge from NSU < 30%; mortality rate in NSU < 5%; morbidity rate in NSU < 10%. Data will be submitted directly into a secure online database and analysed by the study's management group. CONCLUSIONS. The audit will determine the contemporary management and outcomes of patients with CSDH in the United Kingdom and Ireland. It will inform national guidelines, clinical practice and future studies in order to improve the outcome of patients with CSDH.
背景。慢性硬膜下血肿(CSDH)是一种常见疾病,其发病率随年龄增长而升高。CSDH引流是最常见的神经外科手术之一;然而,围手术期的最佳管理、手术技术、术后护理以及辅助治疗的作用仍存在争议。目的。我们提议进行一项前瞻性多中心审计,以确立当前的实践、结果以及为未来研究设定全国性基准。方法。将邀请英国和爱尔兰的神经外科单位(NSU)让患者参与此次审计。所有年龄在16岁及以上的原发性或复发性CSDH成年患者均符合纳入条件。结果测量与分析。提议的结果测量指标为:(1)60天内需要再次手术的临床复发情况;(2)从NSU出院时的改良Rankin量表(mRS)评分;(3)NSU内的发病率和死亡率;(4)从NSU出院时的去向;(5)在NSU的住院时间。审计标准源自已发表的系统评价和近期的一项随机试验。提议的标准为临床复发率<20%;从NSU出院时mRS评分不良(4 - 6分)的比例<30%;NSU内的死亡率<5%;NSU内的发病率<10%。数据将直接提交至一个安全的在线数据库,并由研究管理组进行分析。结论。该审计将确定英国和爱尔兰CSDH患者的当代管理方式和治疗结果。它将为国家指南、临床实践和未来研究提供信息,以改善CSDH患者的治疗效果。