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Cyclosporine-A as prevention for graft-versus-host disease in pediatric patients undergoing bone marrow transplants.

作者信息

Truog A W, Wozniak S P

出版信息

Oncol Nurs Forum. 1990 Jan-Feb;17(1):39-44.

PMID:2405360
Abstract

Cyclosporine-A is a drug commonly used in bone marrow transplantation (BMT) for the prevention of graft-versus-host disease. In the pediatric allogeneic BMT population at The Children's Hospital in Boston, a combination of Cyclosporine-A and Methotrexate is used for graft-versus-host prophylaxis. Graft-versus-host disease, whether acute or chronic, may be fatal. The increasing use of Cyclosporine-A in the pediatric BMT setting demands careful nursing assessment and intervention for Cyclosporine-A toxicity and related side effects.

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