钯催化的硝基（五氟硫基）苯与芳基溴化物的直接芳基化反应。
Pd-catalyzed direct arylation of nitro(pentafluorosulfanyl)benzenes with aryl bromides.
机构信息
Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.
出版信息
Org Lett. 2013 Oct 4;15(19):5004-7. doi: 10.1021/ol4023326. Epub 2013 Sep 20.
Limited methods for the synthesis of SF5-substituted compounds significantly restrict their widespread application. A Pd-catalyzed direct arylation of nitro(pentafluorosulfanyl)benzenes with aryl bromides is reported. This protocol provides a facile and straightforward access to diversified SF5-containing aryl derivatives. The notable features of this reaction are its synthetic simplicity, high reaction efficiency, and good regioselectivity.
SF5 取代化合物的合成方法有限，这极大地限制了它们的广泛应用。本文报道了一种钯催化的硝基（五氟硫基）苯与芳基溴的直接芳基化反应。该方法为合成各种含 SF5 的芳基衍生物提供了一种简便直接的途径。该反应具有合成简单、反应效率高、区域选择性好等特点。
Zotero 插件