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[严重精神病性产妇的剖宫产与振动疗法:一例报告]

[Cesarean section and sismotherapy in a severe psychotic parturient: A case report].

作者信息

Vermersch C, Smadja S, Amselem O, Gay O, Marcellin L, Gaillard R, Mignon A

机构信息

Département d'anesthésie réanimation, hôpital Cochin, 27, rue Faubourg-Saint-Jacques, 75014 Paris, France.

出版信息

Ann Fr Anesth Reanim. 2013 Oct;32(10):711-4. doi: 10.1016/j.annfar.2013.07.808. Epub 2013 Sep 17.

Abstract

Psychiatric disorders may complicate the pregnancy and is one of the causes of maternal and fetal morbidity. We report the case of a patient with severe decompensated schizophrenia during her pregnancy that required prolonged hospitalization in psychiatric ward. The psychiatric status of the patient required the realization of a caesarean section at 36 weeks of amenorrhea. In our case, we decided to perform this cesarean section under general anaesthesia, since regional anaesthesia was not feasible in this patient in a state of uncontrolled agitation. Moreover, general anaesthesia permitted to combine cesarean section with a first session of electroconvulsive therapy, which had been declined during pregnancy. Given the huge amount of antipsychotic agents administered to the patient, we also studied their transplacental transfer and found a very high loxapine concentration in the fetus. Finally, this case raised several important ethical issues related to the management of the mother and her fetus in case of severe psychiatric disorders.

摘要

精神障碍可能使妊娠复杂化,并且是孕产妇和胎儿发病的原因之一。我们报告一例妊娠期间患有严重失代偿性精神分裂症的患者,该患者需要在精神科病房长期住院治疗。患者的精神状态要求在闭经36周时实施剖宫产。在我们的病例中,我们决定在全身麻醉下进行剖宫产,因为该患者处于无法控制的躁动状态,区域麻醉不可行。此外,全身麻醉允许在剖宫产的同时进行首次电休克治疗,而该治疗在孕期被拒绝。鉴于给该患者使用了大量抗精神病药物,我们还研究了这些药物的经胎盘转运情况,发现胎儿体内洛沙平浓度非常高。最后,该病例引发了几个与严重精神障碍情况下母亲及其胎儿管理相关的重要伦理问题。

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