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“Uro-Net”网篮结石嵌顿是否提高经皮肾镜取石术和膀胱结石碎石术的钬激光碎石效率?一项体外研究。

Does stone entrapment with ″Uro-Net″ improve Ho:YAG laser lithotripsy efficiency in percutaneous nephrolithotomy and cystolithopaxy?: an in vitro study.

机构信息

Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

出版信息

Int Braz J Urol. 2013 Jul-Aug;39(4):579-86. doi: 10.1590/S1677-5538.IBJU.2013.04.17.

Abstract

PURPOSE

to test the effect of stone entrapment on laser lithotripsy efficiency.

MATERIALS AND METHODS

Spherical stone phantoms were created using the BegoStone® plaster. Lithotripsy of one stone (1.0 g) per test jar was performed with Ho:YAG laser (365 µm fiber; 1 minute/trial). Four laser settings were tested: I-0.8 J,8 Hz; II-0.2J,50 Hz; III-0.5 J,50 Hz; IV-1.5 J,40 Hz. Uro-Net (US Endoscopy) deployment was used in 3/9 trials. Post-treatment, stone fragments were strained though a 1mm sieve; after a 7-day drying period fragments and unfragmented stone were weighed. Uro-Net nylon mesh and wire frame resistance were tested (laser fired for 30s). All nets used were evaluated for functionality and strength (compared to 10 new nets). Student's T test was used to compare the studied parameters; significance was set at p < 0.05.

RESULTS

Laser settings I and II caused less damage to the net overall; the mesh and wire frame had worst injuries with setting IV; setting III had an intermediate outcome; 42% of nets were rendered unusable and excluded from strength analysis. There was no difference in mean strength between used functional nets and non-used devices (8.05 vs. 7.45 lbs, respectively; p = 0.14). Setting IV was the most efficient for lithotripsy (1.9 ± 0.6 mg/s; p < 0.001) with or without net stabilization; setting III was superior to I and II only if a net was not used.

CONCLUSIONS

Laser lithotripsy is not optimized by stone entrapment with a net retrieval device which may be damaged by high energy laser settings.

摘要

目的

测试结石嵌顿对激光碎石效率的影响。

材料和方法

使用 BegoStone®石膏制作球形结石模型。每个测试罐进行一次激光碎石(1 分钟/次),每次碎石 1 个结石(1.0g)。测试了四种激光设置:I-0.8J,8Hz;II-0.2J,50Hz;III-0.5J,50Hz;IV-1.5J,40Hz。在 3/9 次试验中使用了 Uro-Net(美国内镜)部署。治疗后,通过 1mm 筛过滤结石碎片;在 7 天干燥期后,称重碎片和未碎结石。测试了 Uro-Net 尼龙网和金属丝框架的阻力(激光发射 30s)。评估了所有使用的网的功能和强度(与 10 个新网进行比较)。采用 Student's T 检验比较研究参数;显著性水平设置为 p<0.05。

结果

总体而言,设置 I 和 II 对网的损伤较小;设置 IV 导致网的网格和金属丝框架损伤最严重;设置 III 损伤居中;42%的网无法使用,排除在强度分析之外。使用中的功能网与未使用的装置之间的平均强度无差异(分别为 8.05 和 7.45 磅,p=0.14)。设置 IV 无论是否使用网稳定装置,对碎石术都是最有效的(1.9±0.6mg/s;p<0.001);仅在不使用网的情况下,设置 III 优于 I 和 II。

结论

使用网回收装置进行结石嵌顿并不能优化激光碎石术,因为高能量激光设置可能会损坏网。

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