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经锁骨入路甲状腺切除术后皮肤切口的缝合:组织粘合剂与缝线的比较。

Closure of skin incision after thyroidectomy through a supraclavicular approach: a comparison between tissue adhesive and staples.

机构信息

Department of Breast Surgery, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.

出版信息

Scand J Surg. 2013;102(4):234-40. doi: 10.1177/1457496913490610. Epub 2013 Sep 20.

Abstract

BACKGROUND

The objective of this study was to compare the effectiveness and cosmetic results of tissue adhesive or surgical staples in thyroidectomy through a supraclavicular incision.

METHODS

This was a prospective, randomized study of consecutive patients undergoing thyroidectomy by a supraclavicular approach. Eligible patients were randomized into two groups: one group had the incision closed with tissue adhesive (the experimental group) and the other with surgical staples (the control group). The main outcomes included operative time, early postoperative pain measured by Visual Analog Scale, incidence of wound dehiscence and infection, perceived cosmetic outcome, and overall patient satisfaction by using Patient Satisfaction Assessment Form.

RESULTS

There were 151 consecutive patients assessed for eligibility, and 132 patients were enrolled over 22 months. The clinical characteristics of the patients in the two groups were similar. Main outcomes were assessed in the first 24 h postoperatively, the first month, and the third month postoperatively. Operation time was longer in the experimental group (P = 0.027). Mean Visual Analog Scale scores for pain were lower in the experimental group in the early postoperative period (P < 0.001). No patients developed surgical site infections or wound dehiscence. Lower scores for scar assessment and higher overall satisfaction levels at the first month after surgery were found in the experimental group compared to the control group (P < 0.001). There was no significant difference between the two groups at the third month postoperatively in perceived cosmetic result (P = 0.052) or overall satisfaction (P = 0.059).

CONCLUSIONS

Tissue adhesive is effective and reliable in skin closure for thyroid surgery. While this closure may take somewhat longer to perform, it leads to less postoperative pain, more acceptable wound cosmesis, and higher patient satisfaction levels in short postoperative follow-up.

摘要

背景

本研究旨在比较经锁骨入路甲状腺切除术使用组织粘合剂或手术缝合钉的有效性和美容效果。

方法

这是一项连续患者接受锁骨入路甲状腺切除术的前瞻性、随机研究。符合条件的患者被随机分为两组:一组用组织粘合剂(实验组)关闭切口,另一组用手术缝合钉(对照组)。主要结果包括手术时间、术后早期视觉模拟量表(VAS)评估的疼痛发生率、伤口裂开和感染的发生率、感知的美容效果以及使用患者满意度评估表的总体患者满意度。

结果

共有 151 例连续患者符合纳入标准,在 22 个月内纳入了 132 例患者。两组患者的临床特征相似。主要结果在术后 24 小时内、术后第一个月和第三个月进行评估。实验组的手术时间较长(P = 0.027)。实验组术后早期 VAS 疼痛评分较低(P < 0.001)。两组均未发生手术部位感染或伤口裂开。实验组术后第一个月的疤痕评估评分较低,整体满意度较高(P < 0.001)。术后第三个月,两组在美容效果(P = 0.052)或整体满意度(P = 0.059)方面无显著差异。

结论

组织粘合剂在甲状腺手术皮肤缝合中有效且可靠。虽然这种闭合可能需要更长的时间,但它导致术后疼痛减轻、伤口美容效果更可接受、患者满意度更高。

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