School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 400044, China.
Org Biomol Chem. 2013 Nov 14;11(42):7334-41. doi: 10.1039/c3ob41629a.
Biologically active 3H-pyrrolo[2,3-c]quinolin-4(5H)-ones have been synthesized in an efficient and concise manner utilizing readily available 4-hydroxyquinolin-2(1H)-ones as the starting material. The key strategy relies on the construction of the pyrrole ring through the palladium catalyzed sequential cross-coupling reaction and cyclization process.
生物活性 3H-吡咯并[2,3-c]喹啉-4(5H)-酮已通过利用易得的 4-羟基喹啉-2(1H)-酮作为起始原料，以高效简洁的方式合成。关键策略依赖于通过钯催化的顺序交叉偶联反应和环化过程构建吡咯环。
