Heman-Ackah Selena E, Huang Tina C
Department of Otolaryngology-Head and Neck Surgery, University of Minnesota, MMC 396, 420 Delaware Ave., SE, Minneapolis, MN 55455, USA.
Ear Nose Throat J. 2013 Sep;92(9):430-4.
We report the unique finding of a petrous apex cholesterol granuloma associated with a paraganglioma, also known as a glomus jugulare tumor, in a 52-year-old woman who presented to our department with pulsatile tinnitus, hearing loss, aural fullness, and disequilibrium. She had been treated for a petrous apex cholesterol granuloma 20 years earlier, at which time she had undergone drainage of the granuloma via subtotal petrous apicectomy. When she came to our facility approximately 20 years later, she had signs and symptoms consistent with a jugular paraganglioma, which was likely to have been present at the time of her initial presentation for the cholesterol granuloma. In fact, microscopic bleeding from the paraganglioma might have led to the formation of the cholesterol granuloma. The metachronous presentation of these two entities, which to our knowledge has not been reported previously in the literature, indicates the potential association of paragangliomas with the formation of cholesterol granulomas of the petrous apex.
我们报告了一例独特的病例,一名52岁女性患有岩尖胆固醇肉芽肿并伴有副神经节瘤(也称为颈静脉球瘤),该患者因搏动性耳鸣、听力损失、耳闷和平衡失调前来我院就诊。20年前她曾接受过岩尖胆固醇肉芽肿治疗,当时通过次全岩尖切除术对肉芽肿进行了引流。大约20年后她来到我院时,出现了与颈静脉副神经节瘤相符的体征和症状,很可能在她最初因胆固醇肉芽肿就诊时就已存在。事实上,副神经节瘤的微小出血可能导致了胆固醇肉芽肿的形成。据我们所知,这两种病变的异时出现此前在文献中尚未有报道,提示副神经节瘤与岩尖胆固醇肉芽肿形成之间可能存在关联。