首次使用Integra™人工皮肤在开放性胎儿脊髓脊膜膨出宫内修复术中闭合大面积胎儿皮肤缺损。
Premiere use of Integra™ artificial skin to close an extensive fetal skin defect during open in utero repair of myelomeningocele.
作者信息
Meuli Martin, Meuli-Simmen Claudia, Flake Alan W, Zimmermann Roland, Ochsenbein Nicole, Scheer Ianina, Mazzone Luca, Moehrlen Ueli
机构信息
The Zurich Center for Fetal Diagnosis and Therapy, Zurich, Switzerland,
出版信息
Pediatr Surg Int. 2013 Dec;29(12):1321-6. doi: 10.1007/s00383-013-3412-7. Epub 2013 Sep 22.
BACKGROUND
There are fetuses demonstrating very large myelomeningocele lesion which can not be covered with autochothonous skin.
MATERIAL AND METHODS
We use Integra™ artificial skin for intrauterine coverage of the back lesion. A reverse latissimus dorsi flap was used postnatally to reinforce the repair site.
CONCLUSION
Integra™ appears to be a suitable coverage for large soft tissue defects in utero. Moreover, a postnatal reverse latissimus dorsi flap appears to markedly strengthen tissue coverage over a spinal cord rescued in utero.
背景
存在一些胎儿，其脊柱裂脊髓脊膜膨出病变非常大，无法用自体皮肤覆盖。
材料与方法
我们使用Integra™人工皮肤对背部病变进行宫内覆盖。出生后使用背阔肌肌皮瓣翻转术加强修复部位。
结论
Integra™似乎适合用于子宫内大的软组织缺损的覆盖。此外，出生后的背阔肌肌皮瓣翻转术似乎能显著加强对子宫内挽救的脊髓的组织覆盖。
Zotero 插件