Zheng J-S, Yu Y, Yang J, Xu X-J, Hu X-J, Luo M, Li D
Zhejiang University Department of Food Science and Nutrition Hangzhou China.
Acta Physiol Hung. 2013 Sep;100(3):302-11. doi: 10.1556/APhysiol.100.2013.3.6.
The aim of this study was to investigate postprandial effects of two Chinese liquors on s elected cardiovascular disease risk factors in humans. Sixteen healthy men were randomized into three groups in a three-way crossover study: tea-flavor liquor (TFL), traditional Chinese liquor (TCL) and water control (WC). Every subject consumed 60 mL of either liquor (45% (v/v) ethanol) or water together with a high-fat meal, respectively. Compared with baseline, serum uric acid was significantly increased in TFL group (0.5-hour: P = 0.012; 1-hour: P = 0.001; 2-hour: P = 0.008) and it was significantly decreased in WC group (1-hour: P = 0.001; 2-hour: P = 0.001; 4-hour: P < 0.001), while uric acid was non-significantly increased in the TCL group. High-sensitive C-reactive protein (hs-CRP) was significantly increased in the TCL (P = 0.014) and WC (P = 0.008) groups at postprandial 4 hours compared with baseline. There was no significant difference between groups during the postprandial period for these two parameters or other biochemical parameters. In conclusion, both liquors increased postprandial uric acid, and no significant difference was observed for the effects of TFL and TCL on the measured biochemical parameters.
本研究旨在探讨两种中国白酒对人体选定心血管疾病危险因素的餐后影响。在一项三交叉研究中,16名健康男性被随机分为三组:茶香型白酒(TFL)组、传统中国白酒(TCL)组和水对照组(WC)。每位受试者分别饮用60毫升白酒(45%(v/v)乙醇)或水,并搭配高脂餐。与基线相比,TFL组血清尿酸显著升高(0.5小时:P = 0.012;1小时:P = 0.001;2小时:P = 0.008),WC组血清尿酸显著降低(1小时:P = 0.001;2小时:P = 0.001;4小时:P < 0.001),而TCL组尿酸升高不显著。餐后4小时,TCL组(P = 0.014)和WC组(P = 0.008)的高敏C反应蛋白(hs-CRP)较基线显著升高。餐后期间,这两个参数或其他生化参数在各组之间无显著差异。总之,两种白酒均使餐后尿酸升高,TFL和TCL对所测生化参数的影响未观察到显著差异。