Lichtenberg Michael, Stahlhoff Friedrich-Wilhelm, Boese Dirk
Arnsberg Clinic, Vascular Center, Arnsberg, Germany.
Cardiovasc Revasc Med. 2013 Nov-Dec;14(6):343-8. doi: 10.1016/j.carrev.2013.08.005. Epub 2013 Sep 21.
Acute and subacute ischemia of the lower extremity is still a common reason for amputation. The treatment of this condition includes the well known procedure of local thrombolysis, surgical thrombectomy and, in recent times, percutaneous mechanical thrombectomy procedures such as rotational thrombectomy. However, in randomized studies Fogarty's procedure of surgical thrombectomy was associated with a high rate of perioperative complications and, in part, low technical success rates. On the other hand, local thrombolysis is associated with hemorrhage as well as high costs because of measures requiring substantial resources, such as intensive care monitoring or repeat angiographies. In several studies, the endovascular therapy options of Straub Rotarex® and Aspirex® systems, both products of technical advancements in the field, were shown to be successful in terms of amputation-free survival. Their use was also associated with low complication rates. The majority of studies were focused on arterial blood flow in the femur. However, in the meantime several registers and studies have shown that the systems can also be effectively used to treat proximal deep vein thrombosis. In the present report we review the current study-based value of rotational thrombectomy in the venous and arterial system.
下肢急性和亚急性缺血仍然是截肢的常见原因。这种病症的治疗方法包括众所周知的局部溶栓、外科血栓切除术,以及近年来出现的经皮机械血栓切除术,如旋转血栓切除术。然而,在随机研究中,Fogarty外科血栓切除术与围手术期并发症的高发生率相关,且部分技术成功率较低。另一方面,局部溶栓与出血以及高成本相关,因为需要大量资源的措施,如重症监护监测或重复血管造影。在多项研究中,Straub Rotarex®和Aspirex®系统这两种该领域技术进步的产物,在无截肢生存率方面显示出治疗成功。它们的使用还与低并发症发生率相关。大多数研究集中在股骨的动脉血流。然而,与此同时,一些登记和研究表明,这些系统也可有效用于治疗近端深静脉血栓形成。在本报告中,我们回顾了旋转血栓切除术在静脉和动脉系统中基于研究的当前价值。