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中国家养动物中金刚烷胺耐药性流感 A 病毒的出现和再现的观点。

Perspective on emergence and re-emergence of amantadine resistant influenza A viruses in domestic animals in China.

机构信息

College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 300045, China; Pathogen Diagnostic Center, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200025, China; Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, MS 39762, USA.

出版信息

Infect Genet Evol. 2013 Dec;20:298-303. doi: 10.1016/j.meegid.2013.09.004. Epub 2013 Sep 20.

Abstract

In China, approximately 20% of the animal original influenza A viruses have molecular markers of amantadine resistance. Through phylogenetic data analyses and geospatial statistical analyses, this study suggests emergence of amantadine resistance in animal influenza could be due to selection pressures in China, for example, amantadine usage in some areas.

摘要

在中国,大约 20%的动物源性甲型流感病毒具有金刚烷胺耐药性的分子标记。通过系统进化数据分析和地理空间统计分析,本研究表明,动物流感中金刚烷胺耐药性的出现可能是由于中国的选择压力,例如在某些地区使用金刚烷胺。

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