Scheich Matthias, Ginzkey Christian, Reuter Edith, Harnisch Wilma, Ehrmann Desiree, Hagen Rudolf
Department of Oto-Rhino-Laryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, University Hospital of Wuerzburg, Josef-Schneider-Strasse 11, 97080, Wuerzburg, Germany,
Eur Arch Otorhinolaryngol. 2014 Jul;271(7):1909-16. doi: 10.1007/s00405-013-2671-1. Epub 2013 Sep 6.
The aim of this study was to analyse the quality of life (QOL) of patients who had undergone microsurgery for vestibular schwannomas (VS). A questionnaire was sent to 117 consecutive patients who had been operated on using the middle cranial fossa (MCF) approach between October 2005 and June 2011. The response rate was 91/117 (78%) of which 86 were suitable for analysis. The questionnaire consisted of the Short Form-36 (SF-36) Health Survey including a self-designed, disease-specific section. Demographic data, tumour size, hearing status and facial nerve function were extracted from our VS database. Patients scored significantly lower in seven of the eight subscales of the SF-36 compared to German normative QOL data. But when compared to a normative group of patients with hearing loss, only two subscales were affected. The alteration of the subscales was correlated with objective and subjective parameters. Vertigo and postoperative hearing status could be identified as the parameters with the strongest influence on QOL.
本研究的目的是分析接受前庭神经鞘瘤(VS)显微手术患者的生活质量(QOL)。向2005年10月至2011年6月期间连续117例采用中颅窝(MCF)入路进行手术的患者发送了问卷。回复率为91/117(78%),其中86例适合分析。问卷包括简短健康调查问卷(SF-36)以及一个自行设计的疾病特异性部分。人口统计学数据、肿瘤大小、听力状况和面神经功能均从我们的VS数据库中提取。与德国生活质量标准数据相比,患者在SF-36的八个子量表中的七个得分显著较低。但与听力损失患者的标准组相比,仅两个子量表受到影响。子量表的改变与客观和主观参数相关。眩晕和术后听力状况可被确定为对生活质量影响最大的参数。