Karnegis J N, Matts J P, Tuna N, Amplatz K
University of Nebraska Medical Center, Omaha.
J Electrocardiol. 1990 Jan;23(1):1-7. doi: 10.1016/0022-0736(90)90144-q.
The cardiac damage caused by a myocardial infarction may be evidenced by abnormal electrocardiographic Q-QS complexes (i.e., Minnesota Q-QS codes) and by impairment of left ventricular function. It has been shown that the level of significance of the Q-QS codes is highly correlated with the extent of left ventricular impairment. This study was directed to quantitating this relationship in subjects with a healed myocardial infarction and expressing it mathematically. Using multiple linear regression analysis, a coefficient value was obtained corresponding to the level of significance of each Q-QS code located in each electrocardiographic cardiac area. The left ventricular ejection fraction was estimated by subtracting the coefficient of the most significant code present in each cardiac area from the constant, which was calculated to be the ejection fraction in the absence of any Q-QS code. The results were reproducible, and there was a good correlation between the estimated and measured ejection fraction.
心肌梗死所致的心脏损害可通过异常的心电图Q-QS复合波（即明尼苏达Q-QS编码）以及左心室功能受损得以证实。研究表明，Q-QS编码的显著程度与左心室受损程度高度相关。本研究旨在对心肌梗死已愈合患者的这种关系进行量化，并以数学方式予以表达。通过多元线性回归分析，获得了与位于每个心电图心脏区域的每个Q-QS编码的显著程度相对应的系数值。左心室射血分数是通过从常数中减去每个心脏区域中存在的最显著编码的系数来估算的，该常数经计算为不存在任何Q-QS编码时的射血分数。结果具有可重复性，且估算的射血分数与测量的射血分数之间存在良好的相关性。
