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经皮球囊扩张式主动脉瓣置换术后急性支架回缩的发生率、预测因素及血液动力学后果。

Incidence, predictive factors and haemodynamic consequences of acute stent recoil following transcatheter aortic valve implantation with a balloon-expandable valve.

机构信息

Quebec Heart & Lung Institute, Quebec City, Quebec, Canada.

出版信息

EuroIntervention. 2014;9(12):1398-406. doi: 10.4244/EIJV9I12A237.

DOI:10.4244/EIJV9I12A237
PMID:24064535
Abstract

AIMS

The elastic behaviour (acute recoil) of a valve prosthesis stent following transcatheter aortic valve implantation (TAVI) is unknown. This study sought to determine the occurrence, severity, predictive factors and haemodynamic consequences of acute recoil following TAVI.

METHODS AND RESULTS

A prospective angiographic analysis of the stent frame dimensions in 111 consecutive patients who underwent TAVI with a balloon-expandable valve (36 Edwards SAPIEN; 75 SAPIEN XT) was performed. Acute recoil was defined as the difference between minimal lumen diameter (MLD) at full balloon expansion and immediately after balloon deflation. MLD during balloon inflation was significantly larger than MLD after balloon deflation (23.40±2.31 mm vs. 22.29±2.21 mm, p<0.001), which represented an absolute and percent decrease in stent dimension of 1.10±0.40 mm and 4.70±1.76%, respectively. In the multivariate analysis, the predictors of larger recoil were a higher prosthesis/annulus ratio (r²=0.0624, p=0.015) and the SAPIEN XT prosthesis (r²=0.1276, p=0.001). No significant changes in haemodynamic performance were observed at discharge and follow-up in patients with larger recoil.

CONCLUSIONS

TAVI with a balloon-expandable valve was systematically associated with a certain degree of valve stent recoil after balloon deflation. A higher degree of valve oversizing and the SAPIEN XT prosthesis predicted a larger degree of stent recoil.

摘要

目的

经导管主动脉瓣置换术(TAVI)后瓣膜假体支架的弹性行为(急性回弹)尚不清楚。本研究旨在确定 TAVI 后急性回弹的发生、严重程度、预测因素和血液动力学后果。

方法和结果

对 111 例连续接受球囊扩张瓣膜(36 个 Edwards SAPIEN;75 个 SAPIEN XT)TAVI 的患者进行前瞻性血管造影分析,测量支架框架尺寸。急性回弹定义为球囊完全扩张时的最小管腔直径(MLD)与球囊放气后即刻的差异。球囊扩张期间的 MLD 明显大于球囊放气后的 MLD(23.40±2.31mm 比 22.29±2.21mm,p<0.001),代表支架尺寸的绝对值和百分比减少分别为 1.10±0.40mm 和 4.70±1.76%。多变量分析显示,较大回弹的预测因素是较高的假体/瓣环比值(r²=0.0624,p=0.015)和 SAPIEN XT 假体(r²=0.1276,p=0.001)。在较大回弹的患者中,在出院和随访时未观察到血液动力学性能的显著变化。

结论

经球囊扩张瓣膜的 TAVI 后,球囊放气后瓣膜支架会出现一定程度的回弹。更大程度的瓣膜过度扩张和 SAPIEN XT 假体预测支架更大程度的回弹。

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