根治性子宫颈切除术：宫颈癌年轻女性生育保存的第一步（综述）。
Radical trachelectomy: the first step of fertility preservation in young women with cervical cancer (Review).
机构信息
Department of Women's and Children's Health, University of Padua, Padua, Italy.
出版信息
Oncol Rep. 2013 Dec;30(6):2545-54. doi: 10.3892/or.2013.2736. Epub 2013 Sep 19.
Abstract
Radical trachelectomy (RT) can be performed vaginally or abdominally (laparotomic, laparoscopic or robotic). The aim of this systematic review was to compare all techniques in terms of surgical complications, disease recurrence and subsequent fertility/pregnancy outcomes. A total of 1293 RTs were analyzed (FIGO-stage: IA1-IIA). The most frequent surgical complications do not differ from the ones of radical hysterectomy. The recurrence risk is approximately 3% (range 0-16.8%). The majority of women conceive spontaneously: 284 pregnancies with 173 live births. The most frequent pregnancy complication was miscarriage and chorioamnionitis. RT appears to be a safe option for eligible women who intend to maintain their future pregnancy desire.
摘要
根治性子宫颈切除术（RT）可经阴道或腹部进行（剖腹、腹腔镜或机器人辅助）。本系统评价的目的是比较所有技术在手术并发症、疾病复发和随后的生育/妊娠结局方面的情况。共分析了 1293 例 RT（FIGO 分期：IA1-IIA）。最常见的手术并发症与根治性子宫切除术无差异。复发风险约为 3%（范围 0-16.8%）。大多数妇女自然受孕：284 例妊娠，173 例活产。最常见的妊娠并发症是流产和绒毛膜羊膜炎。对于有保留未来生育愿望的合适女性，RT 似乎是一种安全的选择。
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