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沙特阿拉伯一种濒危药用植物——柳叶布罗尼亚木(茜草科)叶提取物的抗菌活性

Antibacterial activity of leaf extract of Breonadia salicina (Rubiaceae), an endangered medicinal plant of Saudi Arabia.

作者信息

Al-Qurainy F, Z Gaafar Abdel-Rhman, Khan S, Nadeem M, Tarroum M, Alaklabi A, Thomas J

机构信息

Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.

出版信息

Genet Mol Res. 2013 Aug 29;12(3):3212-9. doi: 10.4238/2013.August.29.5.

DOI:10.4238/2013.August.29.5
PMID:24065664
Abstract

Wild plants can contain bioactive compounds with potential activity against disease-causing microorganisms. In the Kingdom of Saudi Arabia, there are many plant species that may have antibacterial, antifungal, or antiviral activities, among other properties. We extracted bioactive compounds with methanol as well as with water from leaves of Breonadia salicina, which is an endangered plant found in the wild in Saudi Arabia. These extracts were tested against the bacteria Bacillus subtilis, Pseudomonas aeruginosa, Shigella sonnei, Escherichia coli, and Staphylococcus aureus. Both extracts showed antibacterial activity against all of the microorganisms, and thus, B. salicina leaf extract has potential as an antimicrobial agent for the preservation of foods, instead of synthetic chemical compounds. We found that the methanolic leaf extract was more effective than the aqueous crude extract against B. subtilis, P. aeruginosa, and S. aureus.

摘要

野生植物可能含有对致病微生物具有潜在活性的生物活性化合物。在沙特阿拉伯王国,有许多植物物种可能具有抗菌、抗真菌或抗病毒活性以及其他特性。我们用甲醇和水从Breonadia salicina的叶子中提取了生物活性化合物,Breonadia salicina是一种在沙特阿拉伯野外发现的濒危植物。这些提取物针对枯草芽孢杆菌、铜绿假单胞菌、宋内志贺菌、大肠杆菌和金黄色葡萄球菌进行了测试。两种提取物对所有微生物均显示出抗菌活性,因此,Breonadia salicina叶提取物作为一种抗菌剂用于食品保鲜具有潜力,可替代合成化学化合物。我们发现,甲醇叶提取物对枯草芽孢杆菌、铜绿假单胞菌和金黄色葡萄球菌的效果比水粗提物更有效。

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