尼日利亚伊巴丹儿童输血相关的艾滋病毒感染

Blood Transfusion-Associated HIV Infection in Children in Ibadan, Nigeria.

作者信息

Brown Biobele J, Oladokun Regina E, Ogunbosi Babatunde O, Osinusi Kikelomo

机构信息

1 Department of Paediatrics, College of Medicine, University of Ibadan, and University College Hospital, Ibadan, Nigeria.

出版信息

J Int Assoc Provid AIDS Care. 2017 May/Jun;16(3):303-308. doi: 10.1177/2325957413500990. Epub 2013 Sep 25.

DOI:10.1177/2325957413500990

PMID:24067495

Abstract

INTRODUCTION

This study describes the epidemiologic features and clinical course of children with blood transfusion-associated HIV infection (TAHI) in Ibadan, Nigeria.

METHODOLOGY

All children diagnosed to have TAHI at the University College Hospital, Ibadan, were studied and compared with children who acquired HIV vertically using the pediatric HIV database in the hospital.

RESULTS

Transfusion-associated HIV infection accounted for 14 (2.3%) of the 597 children diagnosed to have HIV infection between January 2004 and December 2011. The mean age at diagnosis of TAHI was 10.2 years and that of vertically acquired HIV infection was 3.9 years ( P < .001). In 9 cases, blood transfusion took place in private hospitals and in 5 cases in public hospitals. Median interval between infection and diagnosis of AIDS was 84 months in cases with TAHI and 48 months in vertically acquired cases ( P = .542).

CONCLUSION

Optimal blood safety practices are advocated for prevention of TAHI in Nigeria.

摘要

引言

本研究描述了尼日利亚伊巴丹输血相关HIV感染（TAHI）儿童的流行病学特征和临床病程。

方法

对在伊巴丹大学学院医院诊断为TAHI的所有儿童进行研究，并使用该医院的儿科HIV数据库与垂直感染HIV的儿童进行比较。

结果

在2004年1月至2011年12月期间诊断为HIV感染的597名儿童中，输血相关HIV感染占14例（2.3%）。TAHI诊断时的平均年龄为10.2岁，垂直感染HIV的平均年龄为3.9岁（P <.001）。9例在私立医院输血，5例在公立医院输血。TAHI病例从感染到诊断为艾滋病的中位间隔时间为84个月，垂直感染病例为48个月（P =.542）。