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现场记录:美国国防部对多州真菌性脑膜炎疫情的应对措施--2012 年 10 月。

Notes from the field: Department of Defense response to a multistate outbreak of fungal meningitis--United States, October 2012.

出版信息

MMWR Morb Mortal Wkly Rep. 2013 Sep 27;62(38):800-1.

PMID:24067586
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4585540/
Abstract

On October 1, 2012, the Department of Defense (DoD) learned of a multistate outbreak of fungal meningitis in persons who received injections of methylprednisolone acetate (MPA) from a single compounding pharmacy. Ten patients with fungal meningitis after epidural steroid injection (ESI) were initially identified in Tennessee and North Carolina. No military treatment facilities had received MPA from this pharmacy. However, clinics receiving implicated MPA lots were located throughout the United States, and active duty military service members and other DoD health-care beneficiaries could have been exposed through health-care services purchased outside of the DoD health-care system. Therefore, a timely method was needed to determine whether exposure to implicated MPA had occurred among DoD personnel who used purchased care.

摘要

2012 年 10 月 1 日,美国国防部(DoD)获悉一起多州发生的真菌性脑膜炎病例,这些病例均与使用来自一家单一调配药房的甲基强的松龙醋酸酯(MPA)注射液有关。最初在田纳西州和北卡罗来纳州发现了 10 例接受硬膜外皮质类固醇注射(ESI)后患有真菌性脑膜炎的患者。没有军事治疗设施从这家药房接收 MPA。然而,接受受影响 MPA 批次的诊所遍布美国,现役军人和其他国防部医疗保健受益人可能通过国防部医疗保健系统以外购买的医疗服务而受到暴露。因此,需要一种及时的方法来确定在使用外购医疗服务的国防部人员中是否发生了接触受影响 MPA 的情况。

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引用本文的文献

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Disaster Med Public Health Prep. 2016 Feb;10(1):145-51. doi: 10.1017/dmp.2015.137. Epub 2015 Dec 18.

本文引用的文献

1
Fungal infections associated with contaminated methylprednisolone injections.与污染的甲基泼尼松龙注射剂相关的真菌感染。
N Engl J Med. 2013 Oct 24;369(17):1598-609. doi: 10.1056/NEJMoa1213978. Epub 2012 Dec 19.
2
Fungal infections associated with contaminated methylprednisolone in Tennessee.与田纳西州污染的甲基强的松龙相关的真菌感染。
N Engl J Med. 2012 Dec 6;367(23):2194-203. doi: 10.1056/NEJMoa1212972. Epub 2012 Nov 6.
3
Multistate outbreak of fungal infection associated with injection of methylprednisolone acetate solution from a single compounding pharmacy - United States, 2012.2012 年美国单家调配药房供应的醋酸甲泼尼龙注射液引起的真菌感染多州暴发。
MMWR Morb Mortal Wkly Rep. 2012 Oct 19;61(41):839-42.
4
Exophiala infection from contaminated injectable steroids prepared by a compounding pharmacy--United States, July-November 2002.2002年7月至11月美国一家配制药房制备的受污染注射用类固醇引发的外瓶霉感染。
MMWR Morb Mortal Wkly Rep. 2002 Dec 13;51(49):1109-12.