Lavorato Fernanda Guedes, Azulay-Abulafia Luna, Ramos Vanessa, Obadia Daniel Lago, Rocha Diego Santos, Souza Vivian Fichman Monteiro de
Rio de Janeiro(RJ), Brazil.
An Bras Dermatol. 2013 Jul-Aug;88(4):656-8. doi: 10.1590/abd1806-4841.20132251.
Linear Darier is a rare variant of Darier's Disease. The keratotic papules follow Blaschko's lines, characterizing the cutaneous mosaicism. We report the case of a 42-year-old woman who presented with small, linearly distributed, reddish-brown papules on the left mammary region, from the left flank to the hypogastrium and on the pretibial area of the left leg. Histologically, suprabasal acantholysis and dyskeratotic cells were seen, confirming the diagnosis.
线状 Darier 病是 Darier 病的一种罕见变异型。角化丘疹沿 Blaschko 线分布，这是皮肤镶嵌现象的特征。我们报告一例 42 岁女性病例，其左乳区、从左腰到下腹以及左腿胫前区出现小的、呈线状分布的红棕色丘疹。组织学检查可见基底层上方棘层松解和角化不良细胞，确诊为此病。
