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使用免疫生物制剂评估银屑病患者的肾功能。

Evaluation of renal function in patients with psoriasis using immunobiologicals.

作者信息

Melgaço Sarah Suyanne Carvalho, Silva Geraldo Bezerra da, Dantas Amanda Maria Menezes, Vasconcelos Ana Mirella Arcanjo, Siqueira Verônica Riquet de, Vieira Ana Patrícia Freitas, Daher Elizabeth de Francesco

机构信息

Fortaleza(CE),Brazil.

出版信息

An Bras Dermatol. 2013 Jul-Aug;88(4):667-9. doi: 10.1590/abd1806-4841.20132035.

DOI:10.1590/abd1806-4841.20132035
PMID:24068151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3760955/
Abstract

The aim of this study was to evaluate renal function in patients with psoriasis using immunobiologicals. A prospective study was conducted with 15 patients with confirmed diagnosis of psoriasis who were starting to use immunobiologicals. The mean age was 41 ± 11 years, with 60% females. The mean time of disease was 11 ± 6.6 years. Significant changes in creatinine and creatinine clearance were not observed in the course of the study. There was an increase in transaminases and a decrease in magnesium levels.

摘要

本研究的目的是评估使用免疫生物制剂的银屑病患者的肾功能。对15例确诊为银屑病且开始使用免疫生物制剂的患者进行了一项前瞻性研究。平均年龄为41±11岁,女性占60%。疾病平均病程为11±6.6年。在研究过程中未观察到肌酐和肌酐清除率的显著变化。转氨酶升高,镁水平降低。

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Evaluation of renal function in patients with psoriasis using immunobiologicals.使用免疫生物制剂评估银屑病患者的肾功能。
An Bras Dermatol. 2013 Jul-Aug;88(4):667-9. doi: 10.1590/abd1806-4841.20132035.
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Acta Derm Venereol. 2011 Jan;91(1):44-9. doi: 10.2340/00015555-0959.
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[Adverse reactions during biological therapy for psoriasis: results of a survey of the Spanish Psoriasis Group].
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本文引用的文献

1
[Psoriasis in the era of biologics].生物制剂时代的银屑病
Acta Med Port. 2010 May-Jun;23(3):493-8. Epub 2010 Jun 14.
2
Extracapillary glomerulonephritis during etanercept treatment for juvenile psoriatic arthritis.依那西普治疗幼年特发性关节炎时并发血管外肾小球肾炎。
Clin Exp Rheumatol. 2010 Jan-Feb;28(1):91-3.
3
[Off-label use of biologic agents in the treatment of dermatosis, Part 1: infliximab and adalimumab].[生物制剂在皮肤病治疗中的超说明书用药,第1部分:英夫利昔单抗和阿达木单抗]
Actas Dermosifiliogr. 2007 Dec;98(10):657-78.
4
Potential complications associated with the use of biologic agents for psoriasis.使用生物制剂治疗银屑病相关的潜在并发症。
Dermatol Clin. 2007 Apr;25(2):207-13, vii. doi: 10.1016/j.det.2007.01.010.
5
Biologic agents in psoriasis.银屑病中的生物制剂
Australas J Dermatol. 2006 Nov;47(4):217-29; quiz 229-30. doi: 10.1111/j.1440-0960.2006.00286.x.
6
Infliximab and nephrotic syndrome.英夫利昔单抗与肾病综合征。
Nephrol Dial Transplant. 2005 Dec;20(12):2824-6. doi: 10.1093/ndt/gfi180. Epub 2005 Oct 4.
7
Overview of biologic agents in medicine and dermatology.医学与皮肤病学中的生物制剂概述。
Semin Cutan Med Surg. 2005 Mar;24(1):2-9. doi: 10.1016/j.sder.2005.01.007.
8
Development of glomerulonephritis during anti-TNF-alpha therapy for rheumatoid arthritis.类风湿关节炎抗TNF-α治疗期间肾小球肾炎的发生
Nephrol Dial Transplant. 2005 Jul;20(7):1400-6. doi: 10.1093/ndt/gfh832. Epub 2005 Apr 19.
9
Renal toxicity associated with disease-modifying antirheumatic drugs used for the treatment of rheumatoid arthritis.与用于治疗类风湿关节炎的改善病情抗风湿药相关的肾毒性。
Semin Arthritis Rheum. 2000 Dec;30(3):196-208. doi: 10.1053/sarh.2000.16641.