Chan Brian P H, Booth Christopher M, Manduch Marosh, Touma Naji J
School of Medicine, Queen's University, Kingston, ON;
Can Urol Assoc J. 2013 Sep-Oct;7(9-10):E587-9. doi: 10.5489/cuaj.169.
We present a case of spontaneous regression of pulmonary metastases from renal cell carcinoma (RCC) with sarcomatoid differentiation, prior to intervention. The patient presented with conventional type RCC with Furhman Grade 4/4 and sarcomatoid differentiation, complicated by pulmonary metastases. Palliative systemic therapy was planned, but prior to the onset of treatment, serial computed tomography scans demonstrated regression of metastatic disease. Spontaneous regression of metastases is rare, but well-documented in conventional clear cell RCC. To the best of our knowledge, this has not previously been described in the setting of sarcomatoid differentiation of the primary tumour.
我们报告一例肾细胞癌（RCC）伴肉瘤样分化的肺转移灶在干预前自发消退的病例。该患者表现为传统型RCC，Fuhrman分级为4/4级且伴有肉瘤样分化，并伴有肺转移。计划进行姑息性全身治疗，但在治疗开始前，系列计算机断层扫描显示转移病灶消退。转移灶的自发消退很罕见，但在传统透明细胞RCC中有充分记录。据我们所知，此前在原发性肿瘤肉瘤样分化的情况下尚未有过此类描述。
