Onsomu Elijah O, Kimani James K, Abuya Benta A, Arif Ahmed A, Moore DaKysha, Duren-Winfield Vanessa, Harwell George
School of Health Sciences, Winston-Salem State University, Winston-Salem, USA.
Afr J Reprod Health. 2013 Jun;17(2):46-57.
The study purpose was to determine the association between sexual debut and HIV sero-status, and factors contributing to a positive HIV sero-status. Retrospective cross-sectional data from the Kenya Demographic and Health Survey-2003 were used. Data on women aged 15-49 (n = 3,273) and men aged 15-54 (n = 2,917) accepting HIV testing were retained from three datasets. Stata version 10.1 was used for analyses, p < 0.05. Nine percent of women and 5% of men tested positive for HIV, of whom 46% and 49%, p < 0.001 were aged 16-21 respectively. After adjusting for confounding, women and men who had sexual debut aged 16-21 were 2.31 (95% CI: 1.52-3.51), p < 0.001 and 1.83 (95% CI: 1.07-3.13), p < 0.05 times more likely to test positive for HIV compared to those who never had sex respectively. Early sexual debut continues to be a major risk factor for acquiring HIV infection later in life, suggesting earlier interventions could have a major impact towards fighting the disease.
该研究的目的是确定首次性行为与艾滋病毒血清学状态之间的关联，以及导致艾滋病毒血清学状态呈阳性的因素。使用了来自2003年肯尼亚人口与健康调查的回顾性横断面数据。从三个数据集中保留了接受艾滋病毒检测的15 - 49岁女性（n = 3273）和15 - 54岁男性（n = 2917）的数据。使用Stata 10.1版本进行分析，p < 0.05。9%的女性和5%的男性艾滋病毒检测呈阳性，其中分别有46%和49%（p < 0.001）年龄在16 - 21岁。在对混杂因素进行调整后，16 - 21岁首次性行为的女性和男性相比从未有过性行为的人，艾滋病毒检测呈阳性的可能性分别高出2.31倍（95%置信区间：1.52 - 3.51），p < 0.001和1.83倍（95%置信区间：1.07 - 3.13），p < 0.05。过早开始性行为仍然是日后感染艾滋病毒的一个主要危险因素，这表明早期干预可能对抗击该疾病产生重大影响。
