Baron B W, Shermeta D W, Ismail M A, Ben-Ami T, Yousefzadeh D, Carlson N, Amarose A P, Esterly J R
Department of Pathology, University of Chicago, Illinois 60637.
Teratology. 1990 Jan;41(1):9-22. doi: 10.1002/tera.1420410103.
The anatomic features of female conjoined twins with the Janiceps type of cephalothoracopagus are described. Abnormalities included bilateral clefts of the alveolar arches, shared rudimentary mandible, high, arched clavicles, multiple rib deformities, single shared foregut and small intestine, absent large intestines, omphalocele, multicystic kidneys, hypoplastic lungs, interconnected aortas and neck vessels, single ovary with elongated uterus in each twin, displaced labia, abnormal segmentation of the vertebrae, spinal dysraphism, diastasis of the symphysis pubis, malrotated lower extremity, bilateral posterior dislocation of the hips, and club feet. There were two hearts with internal anomalies. Both spinal cords had a myelocele in the lumbar region. The abnormalities noted in previous reports of conjoined twins of this type are reviewed and compared. We propose that factors associated with conjoining, dysgenetic (developmental) defects, and deformations resulting from crowding in utero all may have been important in the abnormal development in this case.
描述了具有头部胸部联体（Janiceps型）的女性联体双胞胎的解剖特征。异常情况包括牙槽弓双侧裂、共用的发育不全下颌骨、高拱形锁骨、多处肋骨畸形、单一共用的前肠和小肠、大肠缺失、脐膨出、多囊肾、肺发育不全、主动脉和颈部血管相互连接、每个双胞胎有一个单一卵巢且子宫细长、阴唇移位、椎体异常分割、脊柱裂、耻骨联合分离、下肢旋转不良、双侧髋关节后脱位和马蹄内翻足。有两颗心脏存在内部异常。两条脊髓在腰部均有脊髓脊膜膨出。回顾并比较了此前关于此类联体双胞胎报告中所提及的异常情况。我们提出，与联体相关的因素、发育不全（发育性）缺陷以及子宫内拥挤导致的畸形在该病例的异常发育过程中可能都起到了重要作用。
