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妊娠早期严重蛛网膜下腔出血合并脑静脉血栓形成:一例报告

Severe subarachnoid hemorrhage associated with cerebral venous thrombosis in early pregnancy: a case report.

作者信息

Yamamoto Junkoh, Kakeda Shingo, Takahashi Mayu, Idei Masaru, Nakano Yoshiteru, Soejima Yoshiteru, Saito Takeshi, Akiba Daisuke, Shibata Eiji, Korogi Yukunori, Nishizawa Shigeru

机构信息

Department of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, Japan.

出版信息

J Emerg Med. 2013 Dec;45(6):849-55. doi: 10.1016/j.jemermed.2013.05.063. Epub 2013 Sep 24.

Abstract

BACKGROUND

Cerebral venous thrombosis (CVT) rarely induces subarachnoid hemorrhage (SAH). During late pregnancy and puerperium, CVT is an uncommon but important cause of stroke. However, severe SAH resulting from CVT is extremely rare during early pregnancy.

OBJECTIVE

We report on a rare case of severe SAH due to CVT, and discuss the potential pitfalls of CVT diagnosis in early pregnancy.

CASE REPORT

A 32-year-old pregnant woman (9th week of pregnancy) presented with slight head dullness. Initial magnetic resonance imaging (MRI) revealed focal, abnormal signal intensity in the left thalamus. Nine days later, the patient developed a generalized seizure and severe SAH was detected with computed tomography (CT) scan. MRI and cerebral angiography revealed a completely thrombosed superior sagittal sinus, vein of Galen, straight sinus, and right transverse sinus. Transvaginal sonography indicated a missed abortion. The day after admission, the patient presented again with a progressive loss of consciousness and signs of herniation. The patient underwent emergency decompressive craniotomy, followed by intrauterine curettage. Two months later, she made an excellent recovery except for a slight visual field defect.

CONCLUSIONS

A rare case of severe SAH due to CVT is reported, with emphasis on the potential pitfalls of CVT diagnosis in early pregnancy.

摘要

背景

脑静脉血栓形成(CVT)很少引起蛛网膜下腔出血(SAH)。在妊娠晚期和产褥期,CVT是一种不常见但重要的中风病因。然而,在妊娠早期,由CVT导致的严重SAH极为罕见。

目的

我们报告一例因CVT导致严重SAH的罕见病例,并讨论妊娠早期CVT诊断中可能存在的陷阱。

病例报告

一名32岁孕妇(妊娠第9周)出现轻微头部闷痛。最初的磁共振成像(MRI)显示左侧丘脑有局灶性异常信号强度。九天后,患者发生全身性癫痫发作,计算机断层扫描(CT)显示严重SAH。MRI和脑血管造影显示上矢状窦、大脑大静脉、直窦和右侧横窦完全血栓形成。经阴道超声检查提示稽留流产。入院次日,患者再次出现意识进行性丧失和脑疝迹象。患者接受了紧急减压开颅手术,随后进行了清宫术。两个月后,除轻微视野缺损外,她恢复良好。

结论

报告了一例因CVT导致严重SAH的罕见病例,重点强调了妊娠早期CVT诊断中可能存在的陷阱。

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