Review of the validity of national coronary heart disease mortality rates.

Epidemiologic studies of coronary heart disease are heavily dependent on national mortality rates. The diagnostic error for the coronary heart disease is substantial but unquantifiable and is conservatively at least +/- 30%. When this error is superimposed on innumerable errors and omissions in the compilation of monocausal mortality rates, the reliability of such vital statistics currently precludes their use for scientific purposes.