Department of Health Behavior and Health Education, University of Arkansas for Medical Sciences, 4301 West Markham Street #820, Little Rock, AR 72205-7199 USA.
Transl Behav Med. 2011 Jun;1(2):224-33. doi: 10.1007/s13142-011-0018-2.
Disparities in breast cancer survival rates suggest that biological processes contribute. Translational research addressing health disparities would benefit from using a community-based participatory approach (CBPR) to examine biological processes commonly seen as the proximal causes of illness as well as behavioral and social-ecological "causes of the causes" within an integrated conceptual framework. This paper describes a CBPR study that explored perceptions regarding breast cancer relevant behaviors, and the application of the study's results to develop translational research. Data from eight focus groups of African American (n = 29) and Caucasian women (n = 27) were analyzed, using the framework of the social-ecological model. Nutrition and physical activity were valued over screening and research participation. Treatment of illness was emphasized over prevention. Women's perspectives are presented within a framework that facilitated the collaborative development of translational research to examine associations among biological, behavioral, and societal processes contributing to disparities.
乳腺癌存活率的差异表明生物学过程起到了一定的作用。为了解决健康差异问题，转化研究将受益于采用以社区为基础的参与式方法（CBPR），从综合概念框架的角度来检查通常被视为疾病近端原因的生物学过程，以及行为和社会生态“病因的原因”。本文描述了一项 CBPR 研究，该研究探讨了与乳腺癌相关行为的认知，并将研究结果应用于转化研究。对 8 组非裔美国（n=29）和白种人（n=27）女性的焦点小组数据进行了分析，使用社会生态模型作为框架。营养和体育活动比筛查和研究参与更受重视。强调治疗疾病，而不是预防。女性的观点是在一个框架内提出的，该框架有助于合作制定转化研究，以检查导致差异的生物学、行为和社会过程之间的关联。
