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[一些具有β-阻断活性的芳香肟新衍生物]

[Some new derivatives of aromatic oximes with beta-blocking activity].

作者信息

Martani A, Magli M, Orzalesi G, Selleri R

出版信息

Farmaco Sci. 1975 May;30(5):370-9.

PMID:240738
Abstract

Because of the great importance assumed by beta-blocking agents in recent years, some new derivatives of aromatic oxime ethers, in the syn form, have been synthesized, having the following general structure: The above compounds were obtained by two different methods designed to demonstrate their structure. The results of some pharmacological tests are also reported, in order to give an indication of the real activity of the new compounds synthesized.

摘要

由于近年来β-阻滞剂的重要性日益凸显,已合成了一些顺式芳香肟醚的新衍生物,其具有以下通式结构:上述化合物通过两种不同方法制得,旨在证实其结构。还报道了一些药理试验结果,以便说明所合成新化合物的实际活性。

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