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带膜支架长期留置在隔离性胰腺坏死和胰腺导管分离综合征患者中的后果。

Consequences of long term indwelling transmural stents in patients with walled off pancreatic necrosis & disconnected pancreatic duct syndrome.

机构信息

Department of Gastroenterology, Post Graduate Institute of Medical Education and Research (PGIMER), Sector 12, Chandigarh 160012, India.

出版信息

Pancreatology. 2013 Sep-Oct;13(5):486-90. doi: 10.1016/j.pan.2013.07.284. Epub 2013 Aug 7.

Abstract

INTRODUCTION

There is limited data on the long term consequences and safety profile of long term indwelling transmural stents after successful treatment of walled off pancreatic necrosis (WOPN).

AIM

To retrospectively evaluate consequences of long term indwelling transmural stents in patients with WOPN.

METHODS

The records of patients who underwent endoscopic transmural drainage of WOPN and had disconnected pancreatic duct syndrome (DPDS) were analyzed.

RESULTS

Thirty patients (26 M; mean age 37.1 ± 7.8 years) with long term indwelling transmural stents and DPDS were followed up for a mean of 20.4 ± 12.2 months (range: 3-38 months). The etiology of acute necrotizing pancreatitis was alcohol in 21, gall stones in 7 and idiopathic in 2 patients. In all patients two or three, 7 (17 patients) or 10 Fr (13 patients) 5 cm double pigtail stents were placed. ERCP revealed disconnected PD at the pancreatic head, body and tail region in 22, 7, and 1 patient respectively. Five patients (16.6%) had spontaneous migration of stents (both the stents in four patients and one stent in one patient; 7 Fr in four and 10 Fr in one patient respectively). Stent migration led to recurrence of pancreatic fluid collection (PFC) in one patient whereas in the remaining 4 patients it did not cause any symptoms. There was no recurrence of symptomatic PFC in remaining 25 patients.

CONCLUSION

Long term indwelling transmural stents in patients with WOPN and DPDS seem to be safe and also appear to decrease the risk of PFC recurrence.

摘要

介绍

关于成功治疗胰腺包裹性坏死(WOPN)后长期留置透壁支架的长期后果和安全性概况的数据有限。

目的

回顾性评估 WOPN 患者长期留置透壁支架的后果。

方法

分析接受内镜透壁引流 WOPN 并伴有胰管分离综合征(DPDS)的患者的记录。

结果

30 例(26 例男性;平均年龄 37.1±7.8 岁)长期留置透壁支架和 DPDS 的患者平均随访 20.4±12.2 个月(范围:3-38 个月)。急性坏死性胰腺炎的病因是酒精 21 例,胆结石 7 例,特发性 2 例。在所有患者中,2 或 3 个 7(17 例)或 10Fr(13 例)5cm 双猪尾支架被放置。ERCP 显示胰头部、体部和尾部 22、7 和 1 例分别有分离的 PD。5 例(16.6%)支架自发性迁移(4 例患者均为两个支架,1 例患者为一个支架;4 例患者为 7Fr,1 例患者为 10Fr)。支架迁移导致 1 例患者胰腺液体积聚(PFC)复发,而其余 4 例患者未出现任何症状。其余 25 例患者均未复发有症状的 PFC。

结论

WOPN 和 DPDS 患者长期留置透壁支架似乎是安全的,并且似乎降低了 PFC 复发的风险。

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