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促性腺激素释放激素激动剂对雄性恒河猴(猕猴)性行为的影响。

Effects of a gonadotropin-releasing hormone agonist on sexual behavior in male rhesus monkeys (Macaca mulatta).

作者信息

Turner J J, Copenhaver J M, Herndon J G, Collins D C

机构信息

Division of Neurobiology, Yerkes Regional Primate Research Center, Emory University, Atlanta, Georgia.

出版信息

Fertil Steril. 1990 Mar;53(3):578-80.

PMID:2407569
Abstract

Low levels of sexual behavior persist in male rhesus monkeys treated with GnRH-a despite very low levels of T and gonadotropin that occur during such treatment. The behavior of male rhesus monkeys treated with GnRH-a resembles the behavior of surgically castrated male rhesus monkeys more closely than it does the behavior of reproductively quiescent males during the normal nonmating season. The normal, seasonal cessation of sexual behavior in male rhesus monkeys may result from changes in behavioral sensitivity to circulating androgens.

摘要

尽管在用促性腺激素释放激素类似物(GnRH-a)治疗期间雄性恒河猴的睾酮(T)和促性腺激素水平非常低,但仍存在低水平的性行为。接受GnRH-a治疗的雄性恒河猴的行为与手术去势的雄性恒河猴的行为更为相似,而不像正常非交配季节中生殖静止的雄性恒河猴的行为。雄性恒河猴正常的季节性性行为停止可能是由于行为对循环雄激素敏感性的变化所致。

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