DasGupta K, Jefferson J W
Department of Psychiatry, University of Wisconsin Hospital & Clinics, Madison 53792.
Gen Hosp Psychiatry. 1990 Mar;12(2):83-97. doi: 10.1016/0163-8343(90)90019-9.
Many patients taking lithium for the treatment of mood disorders suffer from concomitant medical illnesses. Because of its effects on multiple organ systems, extra caution is required when lithium is used in the presence of medical illness. Available data regarding the use of lithium in the presence of thyroid, renal, cardiovascular, dermatologic, and respiratory disease as well as in the presence of disorders of glucose and calcium metabolism are reviewed. In addition, recommendations regarding safe use, serum monitoring, and potential drug interactions are discussed.
许多服用锂盐治疗情绪障碍的患者同时患有其他疾病。由于锂盐对多个器官系统有影响,在存在其他疾病的情况下使用锂盐时需要格外谨慎。本文综述了有关在患有甲状腺疾病、肾脏疾病、心血管疾病、皮肤病、呼吸系统疾病以及糖代谢和钙代谢紊乱的情况下使用锂盐的现有数据。此外,还讨论了关于安全使用、血清监测和潜在药物相互作用的建议。