Department of Psychology, Macquarie University, Sydney, NSW, Australia.
J Clin Neurosci. 2013 Nov;20(11):1486-91. doi: 10.1016/j.jocn.2013.04.037. Epub 2013 Sep 26.
Recently, a pattern referred to as accelerated long-term forgetting (ALF) has been described in patients with epilepsy. In ALF, acquisition and retention over standard delayed recall intervals (up to 30 minutes) tend to be intact, but there is an abnormally rapid rate of forgetting over delays of days or weeks. ALF is associated with everyday memory complaints as well as impairments in autobiographical memory, but goes largely undetected by traditional neuropsychological measures. We consider here the characteristics of ALF and possible contributors to its underlying pathophysiology. Overall, a better understanding of this relatively newly recognised memory disorder should improve clinical treatment.
最近，人们在癫痫患者中描述了一种称为加速长期遗忘（ALF）的模式。在 ALF 中，标准延迟回忆间隔（长达 30 分钟）的获取和保留往往完好无损，但在数天或数周的延迟后，遗忘速度异常快。ALF 与日常记忆主诉以及自传体记忆损伤有关，但传统的神经心理学测量方法往往无法检测到。在这里，我们考虑了 ALF 的特征及其潜在病理生理学的可能贡献。总的来说，对这种相对较新的记忆障碍的更好理解应该会改善临床治疗。
