Simonyi Gábor
Szent Imre Egyetemi Oktatókórház Anyagcsere Központ Budapest Tétényi út 12-16. 1115.
Orv Hetil. 2013 Oct 6;154(40):1587-91. doi: 10.1556/OH.2013.29692.
Hypertension is one of the most frequent chronic diseases as well as most important cardiovascular risk factors in developed countries. Blood pressure control to target levels can significantly decrease the risk for development of coronary artery disease, stroke, chronic renal disease and mortality. Adequately maintained blood pressure is very important in high risk patients. In the treatment of hypertension, life style therapy and drug treatment have essential roles. Further, patient adherence plays a significant part of the treatment, too. Importantly, about half of the patients only become adherent to antihypertensive therapy by the end of the first year treatment. Hence, non-adherence of patients is an important cause for resistant hypertension. Adherence is influenced by the complexity of drug regimen and characteristic of drug class, as well as age and gender of patients.
高血压是发达国家最常见的慢性病之一，也是最重要的心血管危险因素。将血压控制在目标水平可显著降低患冠状动脉疾病、中风、慢性肾病的风险及死亡率。在高危患者中，充分维持血压非常重要。在高血压治疗中，生活方式疗法和药物治疗起着关键作用。此外，患者的依从性在治疗中也起着重要作用。重要的是，约一半的患者在第一年治疗结束时才开始坚持抗高血压治疗。因此，患者不依从是顽固性高血压的一个重要原因。依从性受药物治疗方案的复杂性、药物种类的特性以及患者的年龄和性别的影响。
