自主神经发育促进前列腺癌进展。
Autonomic nerve development contributes to prostate cancer progression.
作者信息
Bauman John, McVary Kevin
出版信息
Asian J Androl. 2013 Nov;15(6):713-4. doi: 10.1038/aja.2013.113. Epub 2013 Sep 30.
Abstract
In a significant translational study, Magnon et al. investigated the role that the autonomic nervous system plays in the development and spread of prostate cancer in both mice and human models. The study shows different roles for both branches of the autonomic nervous system, with the sympathetic system promoting early stages of tumorigenesis, and the parasympathetic system promoting cancer dissemination. This information could lead to important new foundations for treatment, therapies and management of prostate cancer.
摘要
在一项重要的转化研究中，马格农等人在小鼠和人类模型中研究了自主神经系统在前列腺癌发生和扩散中所起的作用。该研究表明自主神经系统的两个分支发挥着不同的作用，交感神经系统促进肿瘤发生的早期阶段，而副交感神经系统促进癌症扩散。这些信息可能为前列腺癌的治疗、疗法和管理带来重要的新基础。
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