Voltas Núria, Hernández-Martínez Carmen, Arija Victoria, Aparicio Estefania, Canals Josefa
Child Psychiatry Hum Dev. 2014 Aug;45(4):377-87. doi: 10.1007/s10578-013-0408-4.
The obsessive-compulsive manifestations course was assessed with the Leyton obsessional inventory-child version survey (LOI-CV) in a 3-year prospective study, using a non-clinical sample. From an initial sample of 1,514 school-age children who underwent symptoms screening for obsessive-compulsive, anxiety and depression, 562 subjects (risk group/without risk group) were re-assessed in the 2nd phase and 242 subjects were monitored after 3 years. LOI-CV scores significantly decreased over time independently of age and gender. The prevalence, persistence and incidence for two levels of severity of obsessive–compulsive manifestations ranged between 4.8-30.4%, 9.3-28.4% and 1.1-14.4%, respectively. 34.6-64.5% of obsessive-compulsive symptomatology was predicted by anxiety, depressive and obsessive-compulsive symptoms. For the obsessiveness (less severe form of obsessive-compulsive manifestations), the depressive symptoms were not predictors. Gender and socioeconomic status were not related with obsessive-compulsive manifestations. These data support a substantial continuity of the obsessive-compulsive manifestations and the existence of different levels of severity within the obsessive-compulsive spectrum.
在一项为期3年的前瞻性研究中，使用非临床样本，通过莱顿强迫观念量表儿童版调查（LOI-CV）对强迫表现过程进行了评估。从最初的1514名接受强迫、焦虑和抑郁症状筛查的学龄儿童样本中，562名受试者（风险组/无风险组）在第二阶段进行了重新评估，242名受试者在3年后接受了监测。LOI-CV得分随时间显著下降，与年龄和性别无关。强迫表现两个严重程度水平的患病率、持续率和发病率分别在4.8%-30.4%、9.3%-28.4%和1.1%-14.4%之间。34.6%-64.5%的强迫症状可由焦虑、抑郁和强迫症状预测。对于强迫观念（强迫表现的较轻形式），抑郁症状不是预测因素。性别和社会经济地位与强迫表现无关。这些数据支持了强迫表现的实质性连续性以及强迫谱系内不同严重程度水平的存在。
