Department of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717, USA.
Chem Commun (Camb). 2013 Nov 14;49(88):10412-4. doi: 10.1039/c3cc46517a.
Here we report the use of a self-assembling protein cage to sequester and solubilize recombinant proteins which are usually trafficked to insoluble inclusion bodies. Our results suggest that protein cages can be used as novel vehicles to rescue and produce soluble proteins that are otherwise difficult to obtain using conventional methods.
在这里，我们报告了使用自组装蛋白笼来隔离和溶解通常被运输到不溶性包涵体中的重组蛋白。我们的结果表明，蛋白笼可以用作新型载体来拯救和生产通常难以用传统方法获得的可溶性蛋白。
