Zaproudina Nina, Lipponen Jukka A, Karjalainen Pasi A, Kamshilin Alexei A, Giniatullin Rashid, Närhi Matti
Institute of Biomedicine, University of Eastern Finland, P.O. Box 1627, FIN-70211 Kuopio, Finland; Institute of Dentistry, University of Eastern Finland, P.O. Box 1627, FIN-70211 Kuopio, Finland.
Department of Applied Physics, University of Eastern Finland, Kuopio, Finland.
Auton Neurosci. 2014 Feb;180:70-3. doi: 10.1016/j.autneu.2013.09.001. Epub 2013 Sep 17.
In search for new biomarkers of vascular disturbances accompanying migraine, we compared the facial and hand skin temperatures in 41 women, including 12 migraine patients during the headache-free period and 29 healthy controls. Compared to the controls, the acral skin temperatures were lower in migraineurs, especially in those with right-sided headache. Our findings suggest that migraine is associated with a peripheral coldness possibly due to abnormal autonomic vascular control. The cold nose and hands may represent easily assessable biomarkers of these disorders.
为了寻找偏头痛伴发血管紊乱的新生物标志物，我们比较了41名女性的面部和手部皮肤温度，其中包括12名处于无头痛期的偏头痛患者和29名健康对照者。与对照组相比，偏头痛患者的手足皮肤温度较低，尤其是右侧头痛的患者。我们的研究结果表明，偏头痛可能与外周寒冷有关，这可能是由于自主神经血管控制异常所致。冰冷的鼻子和双手可能是这些紊乱易于评估的生物标志物。
